Kavathiya Kuldeep, Verma Jitesh, Tiwari Umakant, Bhoyar Bharat
PG Scholar, Chaudhary Brahm Prakash Ayurved Charak Sansthan, Khera Dabar, New Delhi, India.
Department of Kaumarbhritya, Chaudhary Brahm Prakash Ayurved Charak Sansthan, Khera Dabar, New Delhi, India.
J Ayurveda Integr Med. 2025 Jun 25;16(4):101149. doi: 10.1016/j.jaim.2025.101149.
Epidermolysis bullosa (EB) is a group of inherited rare skin disorders that causes the skin to become fragile and blister easily due to minor trauma or friction. Blisters can appear anywhere on the body. There are limitations in treating this disease in the conventional system of medicine. This paper elaborates on the case of two siblings who presented with blisters all over the body with itching, discharge, difficulty in walking, and disfigurement of fingers, toes, and feet. Based on Ayurvedic clinical assessment, the condition was diagnosed as Kapha-pitta dominant Tridoshaja Visphota. They were treated through Ayurveda on the line of Visphota (a type of Kushtha/skin disorder) with the use of Dipana (digestion and metabolism-enhancing), Pachana (enhancing digestion), and Mridu Shodhana (mild bio-cleansing) medicines. Both patients have shown improvement with a reduction in EBDASI (Epidermolysis bullosa disease activity and scaring index) from 174 to 45 and 176 to 39, respectively, in the first and second sibling with 4 months of ayurvedic medication. No relapse was seen in both patients during the next one year. The case study is unique as EB is a genetic disorder with limitations in its management in the conventional system of medicine. Moreover, the authors could not find any published case of EB managed through Ayurveda treatment. Thus, it opens new areas of research in the management of EB through traditional systems of medicine like Ayurveda.
大疱性表皮松解症（EB）是一组遗传性罕见皮肤病，由于轻微创伤或摩擦，会导致皮肤变得脆弱并容易出现水疱。水疱可出现在身体的任何部位。在传统医学体系中治疗这种疾病存在局限性。本文详细阐述了两名兄弟姐妹的病例，他们全身出现水疱，伴有瘙痒、渗液、行走困难以及手指、脚趾和足部畸形。根据阿育吠陀临床评估，该病症被诊断为以卡法-皮塔为主导的三体液失调性皮肤破裂症。他们按照皮肤破裂症（一种库什塔/皮肤病）的治疗方法，使用具有促进消化和新陈代谢、增强消化功能以及温和生物净化作用的药物，通过阿育吠陀医学进行治疗。在接受四个月的阿育吠陀药物治疗后，两名患者均有改善，大疱性表皮松解症疾病活动和瘢痕指数（EBDASI）分别从174降至45以及从176降至39。在接下来的一年里，两名患者均未复发。该病例研究具有独特性，因为大疱性表皮松解症是一种遗传性疾病，在传统医学体系中其治疗存在局限性。此外，作者未找到任何通过阿育吠陀治疗治愈大疱性表皮松解症的已发表病例。因此，它为通过阿育吠陀等传统医学体系管理大疱性表皮松解症开辟了新的研究领域。
