Golysheva Anastasia A, Litvinenko Lyudmila V, Ivshina Irina B
Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences, 13 Golev Str., Perm 614081, Russia.
Department of Microbiology and Immunology, Perm State National Research University, 15 Bukirev Street, Perm 614068, Russia.
Microorganisms. 2025 Jun 10;13(6):1350. doi: 10.3390/microorganisms13061350.
Researchers have identified mercury as one of the most toxic environmental pollutants, with deleterious effects on human health and biota. Microorganisms play a key role in the accumulation, degradation, and neutralisation of mercury. Numerous bacteria, fungi, and microalgae possess the mer operon and its homologues, which contain genes responsible for the transport and detoxification of mercury compounds. Mercury-tolerant Microorganisms efficiently convert mercury into less toxic forms. Their tolerance characteristics position them as promising agents for the remediation of ecosystems altered by human activity. This review explores the mechanisms by which microorganisms resist mercury and their potential for biotechnological applications, including eco-friendly and cost-effective bioremediation of mercury-contaminated environments.
研究人员已将汞确定为毒性最强的环境污染物之一,对人类健康和生物群系具有有害影响。微生物在汞的积累、降解和中和过程中起着关键作用。许多细菌、真菌和微藻拥有汞抗性操纵子及其同源物,其中包含负责汞化合物运输和解毒的基因。耐汞微生物能有效地将汞转化为毒性较小的形式。它们的耐受特性使其成为修复因人类活动而改变的生态系统的有前景的媒介。本综述探讨了微生物抵抗汞的机制及其在生物技术应用中的潜力,包括对汞污染环境进行生态友好且经济高效的生物修复。