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颈动脉内膜切除术期间的最佳脑监测:局部麻醉下的神经反应

Optimal cerebral monitoring during carotid endarterectomy: neurologic response under local anesthesia.

作者信息

Evans W E, Hayes J P, Waltke E A, Vermilion B D

出版信息

J Vasc Surg. 1985 Nov;2(6):775-7.

PMID:4057434
Abstract

A prospective series of carotid endarterectomies were performed with patients given local anesthesia in an attempt to determine the efficacy of intraoperative EEG monitoring and/or stump pressure measurements in predicting the need for carotid shunting. Carotid artery stump pressure was measured and EEG changes noted; however, neither low stump pressure nor EEG changes influenced the decision for shunt insertion. A shunt was only used if a neurologic deficit developed during carotid clamping. A total of 134 carotid endarterectomies were done in 121 patients. Sixty-six patients were men and 55 were women with ages ranging from 41 to 88 years. Indications included transient ischemic attacks in 57 (43%), prior stroke in 25 (19%), vertebrobasilar symptoms in nine (6%), and asymptomatic patients with high-grade stenosis, 43 (32%). Thirteen patients (9.7%) developed neurologic deficits following carotid clamping and had shunts inserted. All deficits cleared following shunt insertion. Nine of the 13 had EEG changes, but in four, EEGs were unchanged despite the occurrence of clear-cut neurologic changes. Stump pressure in the 13 patients ranged from 14 to 78 mm Hg. Ten were greater than 24 mm Hg and three were more than 50 mm Hg. In 121 operations no neurologic deficits occurred during carotid clamping and no shunts were inserted. In 13 of these operations, significant EEG changes were noted. Stump pressures in these 13 with EEG changes ranged from 15 to 120 mm Hg. In seven, stump pressure was greater than 50 mm Hg. There were no deaths in the series. Two (1.5%) temporary and one (0.7%) permanent postoperative deficits occurred.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们进行了一系列前瞻性颈动脉内膜切除术,对患者实施局部麻醉,旨在确定术中脑电图(EEG)监测和/或残端压力测量在预测是否需要进行颈动脉分流方面的有效性。测量了颈动脉残端压力并记录了脑电图变化;然而,无论是低残端压力还是脑电图变化都未影响是否插入分流管的决策。只有在颈动脉夹闭期间出现神经功能缺损时才使用分流管。共对121例患者进行了134次颈动脉内膜切除术。其中66例为男性,55例为女性,年龄在41至88岁之间。手术指征包括57例(43%)短暂性脑缺血发作、25例(19%)既往中风、9例(6%)椎基底动脉症状以及43例(32%)无症状的重度狭窄患者。13例患者(9.7%)在颈动脉夹闭后出现神经功能缺损并插入了分流管。分流管插入后所有缺损均消失。13例中有9例脑电图有变化,但4例尽管出现了明确的神经功能变化,脑电图却未改变。13例患者的残端压力在14至78毫米汞柱之间。10例大于24毫米汞柱,3例大于50毫米汞柱。在121例手术中,颈动脉夹闭期间未出现神经功能缺损,也未插入分流管。其中13例手术记录到明显的脑电图变化。这13例脑电图有变化的患者残端压力在15至120毫米汞柱之间。7例残端压力大于50毫米汞柱。该系列中无死亡病例。出现了2例(1.5%)暂时性和1例(0.7%)永久性术后缺损。(摘要截选至250字)

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