Whittemore A D, Kauffman J L, Kohler T R, Mannick J A
Ann Surg. 1983 Jun;197(6):707-13. doi: 10.1097/00000658-198306000-00009.
Controversy continues concerning the advisability of routine shunting, no shunting, or selective shunting during carotid endarterectomy. Because of its reflection of the physiologic state of the end organ, the authors chose routine 18 lead EEG monitoring as a guide to selective shunting and as an indication of adequate shunt function during all carotid endarterectomies performed from December 1977 through July 1982. In that period, 200 patients underwent 219 endarterectomies under general anesthesia and EEG monitoring. Ischemic EEG changes at the time of carotid cross clamping suggested the need for intraluminal shunts in 16% of patients. Insertion of shunts restored the EEG pattern to normal in all instances, although in two patients, adjustment of the shunt was required to maintain this results. EEG changes requiring shunting occurred in 10% of patients with unilateral disease, in 27% of patients with bilateral disease, and in 42% of patients with unilateral stenosis and contralateral occlusion. Twenty-seven patients had small fixed neurologic deficits before operation. Surgery was not delayed in these individuals who demonstrated no increased requirement for shunts and no new postoperative neurologic deficits. In the group of 150 endarterectomies performed as separate procedures, there was one (0.7%) fixed neurologic deficit after operation, one transient deficit (0.7%), and one death (0.7%). Sixty-nine endarterectomies were performed simultaneously with open heart surgery and were associated with one fixed neurologic deficit (1.4%) and two transient deficits (2.9%). All four deaths in this group were attributable to the cardiac surgical procedures. These results indicate that selective shunting based on EEG monitoring permits the safe performance of carotid endarterectomy, even in patients considered to be at high risk for postoperative neurologic deficit.
关于在颈动脉内膜切除术期间进行常规分流、不进行分流或选择性分流的可行性,争议仍在继续。由于其反映终末器官的生理状态,作者选择常规18导联脑电图监测作为选择性分流的指导,并作为1977年12月至1982年7月期间所有颈动脉内膜切除术期间分流功能充足的指标。在此期间,200例患者在全身麻醉和脑电图监测下接受了219次内膜切除术。颈动脉交叉钳夹时的缺血性脑电图变化表明16%的患者需要腔内分流。尽管有两名患者需要调整分流以维持这一结果,但在所有情况下,分流的插入都使脑电图模式恢复正常。需要分流的脑电图变化发生在10%的单侧疾病患者、27%的双侧疾病患者以及42%的单侧狭窄和对侧闭塞患者中。27例患者术前有轻微的固定性神经功能缺损。对于这些患者,手术并未延迟,他们未表现出对分流需求的增加,也没有新的术后神经功能缺损。在作为单独手术进行的150次内膜切除术组中,术后有1例(0.7%)固定性神经功能缺损、1例短暂性缺损(0.7%)和1例死亡(0.7%)。69次内膜切除术与心脏直视手术同时进行,伴有1例固定性神经功能缺损(1.4%)和2例短暂性缺损(2.9%)。该组中的所有4例死亡均归因于心脏外科手术。这些结果表明,基于脑电图监测的选择性分流允许安全地进行颈动脉内膜切除术,即使在被认为术后神经功能缺损风险较高的患者中也是如此。