Baharvand Iran Nia Yahya, Nourolahi Zahra, Goudarzi Fatemeh, Fouladi Roya, Somaghian Shahram Ahmadi, Mohammadi Rasool
Department of Internal Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran.
Caspian J Intern Med. 2025 Mar 21;16(2):314-319. doi: 10.22088/cjim.16.2.314. eCollection 2025 Spring.
The cost of anticancer drugs and their wastage has become a major concern for patients and health policy makers in developing countries. To date, no figures have been reported on the rate of loss of anticancer drugs in Iran. Therefore, we aimed to conduct a real-world analysis on the anticancer drug wastage in a public hospital.
During a 3-month time span, we observationally collected drug information of all patients admitted for receiving anticancer drugs in the inpatient or outpatient unit of chemotherapy center by two oncology nurses. The amount of drug wastage and its financial cost were calculated based on the price approved by the Food and Drug Administration (FDA) of Islamic Republic of Iran (IRI) during the survey period.
A total of 626 patients were admitted for receiving twenty-four injectable anticancer drugs in 2023 infusions. The percentage of total drug wastage was 9.31% (95% CI, 5.90 -12.71%). Overall, these results indicated that the cost of drug wastage in this 3-month period was roughly 31,473 US dollars (USD) and estimated annual cost of wastage was nearly 125,894 USD (5,287,553,080 Iranian Rial).
This is the first report of investigating anticancer drug wastage in Iran. According to this real-world survey, it was shown that the amount of drug wastage in this center is substantial and imposes a heavy financial burden on patients and the health system that need to be taken into account by policy makers.
抗癌药物的成本及其浪费已成为发展中国家患者和卫生政策制定者的主要关切。迄今为止，伊朗尚未报告抗癌药物的损失率。因此，我们旨在对一家公立医院的抗癌药物浪费情况进行真实世界分析。
在3个月的时间跨度内，我们由两名肿瘤学护士通过观察收集了化疗中心住院部或门诊部所有接受抗癌药物治疗患者的药物信息。根据伊朗伊斯兰共和国食品药品监督管理局（IRI）在调查期间批准的价格计算药物浪费量及其财务成本。
2023年共有626名患者接受了24种注射用抗癌药物的输液治疗。药物总浪费率为9.31%（95%置信区间，5.90 - 12.71%）。总体而言，这些结果表明，这3个月期间的药物浪费成本约为31473美元，估计每年的浪费成本近125894美元（5287553080伊朗里亚尔）。
这是伊朗首次关于抗癌药物浪费情况调查的报告。根据这项真实世界调查，结果显示该中心的药物浪费量很大，给患者和卫生系统带来了沉重的经济负担，政策制定者需要予以考虑。
