Otomi Yoichi, Otsuka Hideki, Kasai Ryosuke, Morishita Jo, Miyake Minaho, Minote Ko, Furutani Kohei, Shimomura Mana, Kamei Yushi, Kasai Hiroto, Shinya Takayoshi, Harada Masafumi
Department of Radiology, Tokushima University Hospital, 2-50-1 Kuramoto-Cho, Tokushima, 770-8503, Japan.
Department of Medical Imaging/Nuclear Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Jpn J Radiol. 2025 Jun 27. doi: 10.1007/s11604-025-01822-5.
Pulmonary hypertension encompasses a diverse set of conditions characterized by increased pressure in the pulmonary arteries. Proper classification is crucial for effective diagnosis and treatment. Ventilation-perfusion scintigraphy plays a vital role in imaging, especially in differentiating chronic thromboembolic pulmonary hypertension from other types of pulmonary hypertension. This article reviews the clinical applications of ventilation-perfusion scintigraphy in the classification of pulmonary hypertension, with particular focus on its relevance to groups 1 (pulmonary arterial hypertension), 3 (pulmonary hypertension associated with lung diseases or hypoxia), and 4 (chronic thromboembolic pulmonary hypertension). In addition, it explores recent technological advances and their impact on clinical practice.
肺动脉高压包括一系列以肺动脉压力升高为特征的不同病症。正确分类对于有效诊断和治疗至关重要。通气-灌注闪烁扫描在成像中起着至关重要的作用,特别是在区分慢性血栓栓塞性肺动脉高压与其他类型的肺动脉高压方面。本文综述了通气-灌注闪烁扫描在肺动脉高压分类中的临床应用,特别关注其与第1组(肺动脉高压)、第3组(与肺部疾病或缺氧相关的肺动脉高压)和第4组(慢性血栓栓塞性肺动脉高压)的相关性。此外,还探讨了近期的技术进展及其对临床实践的影响。