Suzuki H, Moriyama S, Matsushima K, Matsumoto K, Iriyama K
Jpn J Surg. 1985 Jul;15(4):324-6. doi: 10.1007/BF02469925.
Cytophotometric DNA analysis of rectal mucosa was carried out in 11 patients with ulcerative colitis, in attempt to determine the proliferative activity of rectal mucosa. There was no significant difference in the mean DNA value, modal DNA value, total variation of DNA content and population of over 3c cells of rectal mucosa between controls and the patients. However, the differential determination of the proliferative activity in the upper, middle and lower thirds of the crypt disclosed that a population of over 3c cells in the upper and middle thirds of the crypt was significantly larger in the patients with longstanding disease than in the controls.
对11例溃疡性结肠炎患者的直肠黏膜进行了细胞光度学DNA分析，以试图确定直肠黏膜的增殖活性。对照组与患者直肠黏膜的平均DNA值、众数DNA值、DNA含量的总变异以及超过3c细胞群体之间无显著差异。然而，对隐窝上、中、下三分之一处增殖活性的差异测定显示，病程较长的患者隐窝上三分之一和中三分之一处超过3c细胞的群体明显大于对照组。
