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钝顶螺旋藻对镉诱导的肉鸡血液生化和组织病理学改变的保护作用。

Protective effects of Spirulina platensis on cadmium-induced hematobiochemical and histopathological alterations in broiler chickens.

作者信息

Kawsar Iffat, Haque Md Iqramul, Azim Md M N, Shuvo Rahimul Islam, Bhuiyan Md Eftakhar Jahan, Mozumder Anandha, Hashem M A, Islam Md Kamrul, Bhuiyan Mohammad Musharraf Uddin, Hossain Md Golzar, Akter Sharmin

机构信息

Department of Physiology, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.

Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.

出版信息

Poult Sci. 2025 Sep;104(9):105466. doi: 10.1016/j.psj.2025.105466. Epub 2025 Jun 23.

Abstract

Cadmium (Cd) is a toxic heavy metal that contaminates the environment and food chain, leading to severe health implications in poultry. This study investigates the protective effects of Spirulina platensis against Cd-induced hematological, biochemical, histopathological, and meat quality alterations in broiler chickens. A total of 100 broiler chickens were randomly assigned to four experimental groups: Control, cadmium (Cd)-treated (75 mg/kg/day), spirulina treated (2 g/kg/day), and a combined Cd + spirulina-treated group. Exposure to cadmium led to a significant reduction in body weight, disruption of hematological profiles, elevation of liver and kidney enzyme levels, and deterioration of meat quality traits. However, co-administration of spirulina effectively mitigated these adverse effects by restoring hematological and biochemical parameters, reducing tissue cadmium accumulation, and improving both histopathological features and meat quality. Based on the findings, Spirulina platensis demonstrates notable potential in alleviating cadmium-related health impairments in broiler chickens.

摘要

镉(Cd)是一种有毒重金属,会污染环境和食物链,对家禽健康产生严重影响。本研究调查了钝顶螺旋藻对镉诱导的肉鸡血液学、生化、组织病理学和肉质改变的保护作用。总共100只肉鸡被随机分为四个实验组:对照组、镉处理组(75毫克/千克/天)、螺旋藻处理组(2克/千克/天)和镉+螺旋藻联合处理组。接触镉导致体重显著下降、血液学指标紊乱、肝肾酶水平升高以及肉质性状恶化。然而,螺旋藻的共同给药通过恢复血液学和生化参数、减少组织镉积累以及改善组织病理学特征和肉质,有效减轻了这些不良反应。基于这些发现,钝顶螺旋藻在减轻肉鸡镉相关健康损害方面显示出显著潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4794/12414276/95916620fc24/gr1.jpg

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