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单纯减压与减压融合治疗高信号小关节腰椎管狭窄症患者的长期疼痛和残疾结局比较

Comparable long-term pain and disability outcomes following decompression alone versus decompression with fusion in lumbar spinal stenosis patients with high-signal facet joints.

作者信息

Cameron Guy John-Malcolm, Garrett Jade Maree, Azzi Anthea Sapphire, Matthews William Colby, Singh Akash Rae, Ferch Richard

机构信息

University of Newcastle Australia, Newcastle, Australia.

Hunter Medical Research Institute, Newcastle, Australia.

出版信息

Eur Spine J. 2025 Jun 28. doi: 10.1007/s00586-025-09065-8.

DOI:10.1007/s00586-025-09065-8
PMID:40580226
Abstract

PURPOSE

This study aimed to evaluate the long-term outcomes of decompressive surgery with or without fusion in patients with lumbar spinal stenosis (LSS) exhibiting high-signal facet joints, a radiological marker of potential instability.

METHODS

A retrospective cohort study analysed surgeries performed by a single surgeon between January 2016 and June 2023. Eligible participants (n = 100) were adults with LSS who underwent decompression with or without fusion and were followed up using validated questionnaires to assess pain (VAS back, VAS leg) and disability (ODI, RMDQ). Statistical analyses included t-tests, ANOVA, and logistic regression to evaluate clinical outcomes.

RESULTS

Fifty-seven patients underwent decompressive surgery (SD), and 43 underwent decompression with fusion (DF). DF patients were younger (67.67 vs. 73.07 years, p = 0.0008) and more likely to exhibit radiological markers of instability, including L5-S1 involvement (p = 0.0315) and Grade 1 spondylolisthesis (p = 0.0118). Both groups showed significant improvements in pain and disability scores (p < 0.0001), with no significant differences between groups at follow-up. DF was associated with longer hospital stays (3.07 vs. 1.70 days, p < 0.0001) but fewer revision surgeries (2.33% vs. 15.79%, p = 0.0402). Higher BMI reduced odds of ODI improvement in the SD group (p = 0.0252), while older age decreased the odds of RMDQ improvement in the DF group (p = 0.0102).

CONCLUSION

Both surgical approaches yielded significant improvements in pain and disability for patients with LSS. The findings suggest fusion may not be necessary for patients with high-signal facet joints absent additional instability markers, supporting a tailored approach to surgical decision-making.

摘要

目的

本研究旨在评估对于腰椎管狭窄症(LSS)患者,有无融合的减压手术的长期疗效,这些患者表现出高信号小关节,这是潜在不稳定的一种影像学标志。

方法

一项回顾性队列研究分析了2016年1月至2023年6月期间由一名外科医生实施的手术。符合条件的参与者(n = 100)为患有LSS的成年人,他们接受了有或无融合的减压手术,并使用经过验证的问卷进行随访,以评估疼痛(腰部视觉模拟评分、腿部视觉模拟评分)和残疾情况(腰椎功能障碍指数、修订版魁北克腰痛残疾量表)。统计分析包括t检验、方差分析和逻辑回归,以评估临床疗效。

结果

57例患者接受了减压手术(SD),43例接受了融合减压手术(DF)。DF组患者更年轻(67.67岁对73.07岁,p = 0.0008),且更有可能表现出不稳定的影像学标志,包括L5-S1节段受累(p = 0.0315)和I度椎体滑脱(p = 0.0118)。两组患者的疼痛和残疾评分均有显著改善(p < 0.0001),随访时两组之间无显著差异。DF与更长的住院时间相关(3.07天对1.70天,p < 0.0001),但翻修手术较少(2.33%对15.79%,p = 0.0402)。较高的体重指数降低了SD组腰椎功能障碍指数改善的几率(p = 0.0252),而年龄较大则降低了DF组修订版魁北克腰痛残疾量表改善的几率(p = 0.0102)。

结论

两种手术方法都使LSS患者的疼痛和残疾情况有显著改善。研究结果表明,对于没有其他不稳定标志的高信号小关节患者,融合手术可能没有必要,这支持了一种针对手术决策的个性化方法。

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本文引用的文献

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J Neurol Neurosurg Psychiatry. 2023 Aug;94(8):657-666. doi: 10.1136/jnnp-2022-330158. Epub 2023 Feb 27.
2
A Simple Preoperative Score Predicting Failure Following Decompression Surgery for Degenerative Lumbar Spinal Stenosis.一种用于预测退行性腰椎管狭窄减压术后失败的简易术前评分。
Spine (Phila Pa 1976). 2023 May 1;48(9):610-616. doi: 10.1097/BRS.0000000000004584. Epub 2023 Jan 19.
3
Decompression Alone Compared to Decompression With Fusion in Patients With Lumbar Spondylolisthesis: Systematic Review, Meta-Analysis, and Meta-Regression.
腰椎滑脱症患者单纯减压与减压融合术的比较:系统评价、荟萃分析和Meta回归分析
Int J Spine Surg. 2022 Feb;16(1):71-80. doi: 10.14444/8179.
4
MRI T2-mapping of lumbar facet joints is effective for quantitative evaluation of lumbar instability in patients with degenerative lumbar disorders.MRI T2-mapping 对腰椎小关节的定量评估有助于退行性腰椎疾病患者腰椎不稳定的诊断。
Eur Spine J. 2022 Jun;31(6):1479-1486. doi: 10.1007/s00586-022-07119-9. Epub 2022 Jan 28.
5
A diagnostic tool for people with lumbar instability: a criterion-related validity study.用于诊断腰椎不稳定人群的工具:一项相关性效研究。
BMC Musculoskelet Disord. 2021 Nov 23;22(1):976. doi: 10.1186/s12891-021-04854-w.
6
Variation in surgical treatment of degenerative spondylolisthesis in Canada: surgeon assessment of stability and impact on treatment.加拿大退行性脊椎滑脱症手术治疗的差异:外科医生对稳定性的评估及其对治疗的影响。
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7
Lumbar degenerative spondylolisthesis: factors associated with the decision to fuse.腰椎退行性滑脱:与融合决策相关的因素。
Spine J. 2021 May;21(5):821-828. doi: 10.1016/j.spinee.2020.11.010. Epub 2020 Nov 26.
8
Fusion Surgery for Lumbar Spinal Stenosis: WFNS Spine Committee Recommendations.腰椎管狭窄症的融合手术:世界神经外科联合会脊柱委员会建议
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Systematic Review of Outcomes Following 10-Year Mark of Spine Patient Outcomes Research Trial (SPORT) for Degenerative Spondylolisthesis.退行性脊椎滑脱症 SPORT 研究试验 10 年随访结果的系统回顾
Spine (Phila Pa 1976). 2020 Jun 15;45(12):820-824. doi: 10.1097/BRS.0000000000003485.