Ikeda H, Tauchi H, Shimasaki H, Ueta N, Sato T
Mech Ageing Dev. 1985 Jul-Aug;31(2):139-46. doi: 10.1016/s0047-6374(85)80024-5.
The amount and distribution of autofluorescent granules in various organs and tissues of rats of different ages (2-, 11-, and 29.5-month-old) were compared by morphometrical analysis. The age-related increase of the granules was observed in the cardiac muscle and hepatic cells, but the amount of granules was little even in 29.5-month-old rats. In some other organs, the granules appeared early, at 2 months of age, increased up to 11 months, but thereafter no significant increase was observed. The autofluorescent granules are not merely considered to be an age-related pigment, but seems to be influenced by relationship to the cell metabolism and other functions.
通过形态计量分析比较了不同年龄(2个月、11个月和29.5个月)大鼠各器官和组织中自发荧光颗粒的数量和分布。在心肌和肝细胞中观察到颗粒数量随年龄增长而增加,但即使在29.5个月大的大鼠中,颗粒数量也很少。在其他一些器官中,颗粒在2个月大时就出现了,到11个月时增加,但此后没有观察到显著增加。自发荧光颗粒不仅被认为是一种与年龄相关的色素,而且似乎受到与细胞代谢和其他功能关系的影响。