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胃肠道手术患者的围手术期营养支持:当前观点及对术前康复措施的强调

Perioperative nutritional support in patients undergoing gastrointestinal surgery: Current views with an emphasis on prehabilitation efforts.

作者信息

Triantafillidis John K

机构信息

Department of Inflammatory Bowel Disease Unit, "Metropolitan General" Hospital, Holargos 15562, Attica, Greece.

出版信息

World J Gastrointest Surg. 2025 Jun 27;17(6):101244. doi: 10.4240/wjgs.v17.i6.101244.

DOI:10.4240/wjgs.v17.i6.101244
PMID:40584482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12188574/
Abstract

Continuously increasing reports in the international medical literature, along with current guidelines from international societies, support the view that perioperative enteral nutrition (EN) and immunonutrition offer significant benefits to patients with benign and/or malignant digestive disorders, including reduction of postoperative infections and hospital stay. A vital component of the rehabilitation of patients after major gastrointestinal surgery is a comprehensive nutritional rehabilitation program. It has been shown that implementing an integrated nutritional support program significantly improves patients' immune responses, accelerates wound healing processes, reduces pain and accompanying anxiety, and decreases hospital length of stay. It appears that, in addition to the efforts of rehabilitation, prehabilitation, the return to the presurgery level of physical fitness, is or should be a vital objective of the team responsible for rehabilitating patients undergoing gastrointestinal surgery. The present review summarized the most up-to-date data on the role of perioperative nutritional support (EN and immune EN) in the rehabilitation and prehabilitation of patients undergoing major digestive surgery. Systematic and comprehensive perioperative nutritional support for these patients should become a daily clinical practice element of paramount importance.

摘要

国际医学文献中不断增加的报道以及国际协会的现行指南均支持这样一种观点,即围手术期肠内营养(EN)和免疫营养对患有良性和/或恶性消化系统疾病的患者具有显著益处,包括减少术后感染和缩短住院时间。大型胃肠道手术后患者康复的一个重要组成部分是全面的营养康复计划。研究表明,实施综合营养支持计划可显著改善患者的免疫反应,加速伤口愈合过程,减轻疼痛及伴随的焦虑,并缩短住院时间。看来,除了康复努力外,术前康复,即恢复到手术前的体能水平,是或应该是负责胃肠道手术患者康复的团队的一个重要目标。本综述总结了围手术期营养支持(EN和免疫EN)在大型消化手术患者康复和术前康复中作用的最新数据。对这些患者进行系统而全面的围手术期营养支持应成为日常临床实践中至关重要的一部分。

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本文引用的文献

1
Effects of comprehensive nutrition support on immune function, wound healing, hospital stay, and mental health in gastrointestinal surgery.综合营养支持对胃肠外科手术患者免疫功能、伤口愈合、住院时间及心理健康的影响
World J Gastrointest Surg. 2024 Dec 27;16(12):3737-3744. doi: 10.4240/wjgs.v16.i12.3737.
2
Prehabilitation Research: A Bibliometric Analysis of Past Trends and Future Directions.术前康复研究:过去趋势与未来方向的文献计量分析
Am J Phys Med Rehabil. 2025 Apr 1;104(4):357-363. doi: 10.1097/PHM.0000000000002611. Epub 2024 Aug 22.
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Gastrointestinal cancer surgery in the elderly: The effects of preoperative oral nutritional supplements - A retrospective study.老年人胃肠癌手术:术前口服营养补充的效果-一项回顾性研究。
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Contemporary Perioperative Nutritional Care.当代围手术期营养护理。
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5
Nutritional Prehabilitation in Patients Undergoing Abdominal Surgery-A Narrative Review.营养预康复在腹部手术患者中的应用:一项叙述性综述。
Nutrients. 2024 Jul 11;16(14):2235. doi: 10.3390/nu16142235.
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Multimodal prehabilitation and postoperative outcomes in upper abdominal surgery: systematic review and meta-analysis.多模态术前康复与上腹部手术后结局:系统评价和荟萃分析。
Sci Rep. 2024 Jul 11;14(1):16012. doi: 10.1038/s41598-024-66633-6.
7
Enteral Nutrition in Operated-On Gastric Cancer Patients: An Update.术后胃癌患者的肠内营养:最新进展。
Nutrients. 2024 May 27;16(11):1639. doi: 10.3390/nu16111639.
8
Surgical treatment of inflammatory bowel disease: From the gastroenterologist's stand-point.炎症性肠病的外科治疗:从胃肠病学家的角度来看
World J Gastrointest Surg. 2024 May 27;16(5):1235-1254. doi: 10.4240/wjgs.v16.i5.1235.
9
10 years of prehabilitation: From theory to clinical practice.10 年的预康复:从理论到临床实践。
Cir Esp (Engl Ed). 2024 Aug;102(8):451-458. doi: 10.1016/j.cireng.2024.04.010. Epub 2024 May 6.
10
A review of perioperative immune-modulating and metabolic-modulating nutrition strategies for bowel resection surgery.肠道切除手术围手术期免疫调节和代谢调节营养策略综述
JPEN J Parenter Enteral Nutr. 2024 Jul;48(5):538-545. doi: 10.1002/jpen.2634. Epub 2024 Apr 30.