Department of IBD and Endoscopy, "Metropolitan General" Hospital, 15562 Holargos, Greece.
Hellenic Society of Gastrointestinal Oncology, 15562 Athens, Greece.
Nutrients. 2024 May 27;16(11):1639. doi: 10.3390/nu16111639.
It is well established that the preoperative nutritional status of gastric cancer (GC) patients significantly affects the prognosis of the operated patients, their overall survival, as well as the disease-specific survival. Existing data support that preoperative assessment of nutritional status and early correction of nutritional deficiencies exert a favorable effect on early postoperative outcomes. A variety of relevant indices are used to assess the nutritional status of GC patients who are candidates for surgery. The guidelines of almost all international organizations recommend the use of oral enteral nutrition (EN). Oncologically acceptable types of gastrectomy and methods of patient rehabilitation should take into account the expected postoperative nutritional status. The majority of data support that perioperative EN reduces complications and hospital stay, but not mortality. Oral EN in the postoperative period, albeit in small amounts, helps to reduce the weight loss that is a consequence of gastrectomy. Iron deficiency with or without anemia and low serum levels of vitamin B12 are common metabolic sequelae after gastrectomy and should be restored. EN also significantly helps patients undergoing neoadjuvant or adjuvant antineoplastic therapy. The occurrence of the so-called "postgastrectomy syndromes" requires dietary modifications and drug support. This review attempts to highlight the benefits of EN in GC patients undergoing gastrectomy and to emphasize the type of necessary nutritional management, based on current literature data.
已经明确的是,胃癌(GC)患者的术前营养状况显著影响手术患者的预后、总体生存率和疾病特异性生存率。现有数据支持术前评估营养状况和早期纠正营养缺乏对术后早期结局有有利影响。多种相关指标用于评估接受手术的 GC 患者的营养状况。几乎所有国际组织的指南都建议使用口服肠内营养(EN)。可接受的肿瘤学胃切除术类型和患者康复方法应考虑预期的术后营养状况。大多数数据支持围手术期 EN 可减少并发症和住院时间,但不降低死亡率。术后口服 EN,即使量很小,也有助于减少胃切除术后的体重减轻。缺铁伴或不伴贫血和低血清维生素 B12 是胃切除术后常见的代谢后遗症,应予以纠正。EN 还可显著帮助接受新辅助或辅助抗肿瘤治疗的患者。所谓“胃切除术后综合征”的发生需要饮食调整和药物支持。这篇综述试图强调接受胃切除术的 GC 患者接受 EN 的益处,并根据当前文献数据强调必要的营养管理类型。