文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

用于评估帕金森病神经功能缺损的标准化临床评估和先进的人工智能驱动工具,包括在基于生物标志物的框架内——人类智能与人工智能模型的比较——系统评价

Standardized clinical assessments and advanced AI-driven instruments used to evaluate neurofunctional deficits, including within biomarker based framework, in Parkinson's disease - human intelligence made vs. AI models - systematic review.

作者信息

Anghelescu Aurelian, Munteanu Constantin, Spinu Aura, Ciobanu Vlad, Popescu Cristina, Cioca Ioana Elena, Andone Ioana, Stoica Simona-Isabelle, Mandu Mihaela, Rebedea Ana, Giuvara Sebastian, Malaelea Alin-Daniel, Vladulescu-Trandafir Andreea-Iulia, Morcov Maria-Veronica, Onose Gelu

机构信息

Department of Specific Discipline, Faculty of Midwifery and Nursing, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.

Teaching Emergency Hospital "Bagdasar-Arseni", Bucharest, Romania.

出版信息

Front Med (Lausanne). 2025 Jun 13;12:1565275. doi: 10.3389/fmed.2025.1565275. eCollection 2025.


DOI:10.3389/fmed.2025.1565275
PMID:40584716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12202485/
Abstract

INTRODUCTION: Considering the extensive development of artificial intelligence (AI) facilities, like Generative Pre-Trained Transformer (ChatGPT) 4.o and ChatGPT Scholar, we explored their abilities to conduct a systematic literature review. Using as a specific domain, an attempt to frame/methodize clinical assessment instruments used to evaluate neuro-functional deficits in Parkinson's disease (PD) - including framed through the ICF(-DH) paradigm - for the above-mentioned comparison between human intelligence (HI) and AI, this paper is as well, a follow-up regarding the most actual subject matter of the AI's capabilities evolution in this respect. As well-known clinical-/paraclinical-/functional evaluations, using assessment quantitative (as much as possible) instruments, are basic endeavors for rehabilitation, as they enable setting of appropriate and realistic therapeutic-rehabilitative specific goals. METHODS: Within the actual work, we have first achieved a narrative synthesis of the main molecular mechanisms involved in PD pathophysiology, underpinning its clinical appearance and evolution. To fundament our knowledge on an up-to-date information regarding the clinical-functional evaluation tools practiced in PD, we systematically reviewed the literature in this domain, published in the last 6 years, through a PRISMA type method for filtering/selecting the related bibliographic resources. The same keywords combinations/syntaxes have been used contextually, also to dialogize with ChatGPT4.o and ChatGPT. RESULTS: Scholar Applying PRISMA type methodology (HI achieved), we have selected, matching the filtering criteria, 24 articles. Interrogating the two AI above-mentioned models, we obtained quite difficult to be availed/useful - comparative to our HI obtained - outcomes. Thus, when interrogating ChatGPT4.o, ChatGPT Scholar repeatedly, they provided - partially diverse - inappropriate related answers, including ones pending on the interrogator's IP, although they claimed to have this capacity. DISCUSSION: We consider, regarding their capabilities to achieve systematic literature reviews, that neither ChatGPT 4.o nor ChatGPT Scholar still cannot succeed this (yet, they keep improving lately). Additionally, we have consistently extended, including within a narrative related literature review, our 'dialogue" with these two AI facilities regarding their availability to enhance the related evaluation instruments accuracy on neurofunctional assessments within biomarker-based frameworks. So, our research aimed basically to emphasize the main topical data regarding these two important paradigms of knowledge (based on HI and on AI) acquirements - considering the impetuous development of the latter - and thus, possibly to contribute inclusively at improving the actual performances to achieve Systematic Literature Reviews through the PRISMA type method - for the moment still better served by HI.

摘要

引言:鉴于人工智能(AI)工具的广泛发展,如生成式预训练变换器(ChatGPT)4.0和ChatGPT Scholar,我们探讨了它们进行系统文献综述的能力。作为一个特定领域,我们试图构建/规范用于评估帕金森病(PD)神经功能缺损的临床评估工具——包括通过国际功能、残疾和健康分类(ICF-DH)范式进行构建——以便在人类智能(HI)和AI之间进行上述比较。本文也是关于AI在这方面能力演变的最前沿主题的后续研究。众所周知,使用评估定量(尽可能)工具进行临床/准临床/功能评估是康复的基本工作,因为它们能够设定适当和现实的治疗康复具体目标。 方法:在实际工作中,我们首先对PD病理生理学中涉及的主要分子机制进行了叙述性综合,这些机制是其临床表现和演变的基础。为了基于有关PD中实践的临床功能评估工具的最新信息来巩固我们的知识,我们通过一种PRISMA类型的方法对过去6年发表的该领域文献进行了系统综述,以筛选/选择相关的文献资源。在上下文中使用了相同的关键词组合/语法,也用于与ChatGPT4.0和ChatGPT进行对话。 结果:应用PRISMA类型方法(人类智能完成),我们筛选出符合筛选标准的24篇文章。询问上述两个AI模型时,与我们人类智能获得的结果相比,我们得到的结果很难有用。因此,当反复询问ChatGPT4.0和ChatGPT Scholar时,它们提供了——部分不同的——不适当的相关答案,包括依赖询问者IP的答案,尽管它们声称具备这种能力。 讨论:关于它们进行系统文献综述的能力,我们认为ChatGPT 4.0和ChatGPT Scholar目前都无法成功做到这一点(不过,它们最近一直在改进)。此外,我们一直在扩展,包括在叙述性相关文献综述中,我们与这两个AI工具就它们在基于生物标志物的框架内提高神经功能评估相关评估工具准确性的可用性进行了“对话”。因此,我们的研究主要旨在强调关于这两种重要知识范式(基于人类智能和基于AI)获取的主要主题数据——考虑到后者的迅猛发展——从而可能全面有助于通过PRISMA类型方法提高实现系统文献综述的实际性能——目前人类智能在这方面仍然表现更佳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/16ad01043ad0/fmed-12-1565275-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/83086fcc82c3/fmed-12-1565275-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/cd55b2cb3eba/fmed-12-1565275-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/71791db39330/fmed-12-1565275-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/5061ceb18c52/fmed-12-1565275-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/16ad01043ad0/fmed-12-1565275-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/83086fcc82c3/fmed-12-1565275-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/cd55b2cb3eba/fmed-12-1565275-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/71791db39330/fmed-12-1565275-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/5061ceb18c52/fmed-12-1565275-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a546/12202485/16ad01043ad0/fmed-12-1565275-g005.jpg

相似文献

[1]
Standardized clinical assessments and advanced AI-driven instruments used to evaluate neurofunctional deficits, including within biomarker based framework, in Parkinson's disease - human intelligence made vs. AI models - systematic review.

Front Med (Lausanne). 2025-6-13

[2]
Prescription of Controlled Substances: Benefits and Risks

2025-1

[3]
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19.

Cochrane Database Syst Rev. 2022-5-20

[4]
Methodologies for assessing morphosyntactic ability in people with Alzheimer's disease.

Int J Lang Commun Disord. 2024

[5]
Cost-effectiveness of using prognostic information to select women with breast cancer for adjuvant systemic therapy.

Health Technol Assess. 2006-9

[6]
Short-Term Memory Impairment

2025-1

[7]
Comparison of Two Modern Survival Prediction Tools, SORG-MLA and METSSS, in Patients With Symptomatic Long-bone Metastases Who Underwent Local Treatment With Surgery Followed by Radiotherapy and With Radiotherapy Alone.

Clin Orthop Relat Res. 2024-12-1

[8]
Eliciting adverse effects data from participants in clinical trials.

Cochrane Database Syst Rev. 2018-1-16

[9]
Survivor, family and professional experiences of psychosocial interventions for sexual abuse and violence: a qualitative evidence synthesis.

Cochrane Database Syst Rev. 2022-10-4

[10]
How lived experiences of illness trajectories, burdens of treatment, and social inequalities shape service user and caregiver participation in health and social care: a theory-informed qualitative evidence synthesis.

Health Soc Care Deliv Res. 2025-6

本文引用的文献

[1]
Role of Glutathione in Parkinson's Disease Pathophysiology and Therapeutic Potential of Polyphenols.

Phytother Res. 2024-12

[2]
Alpha-synuclein, autophagy-lysosomal pathway, and Lewy bodies: Mutations, propagation, aggregation, and the formation of inclusions.

J Biol Chem. 2024-10

[3]
Calcium Deregulation in Neurodegeneration and Neuroinflammation in Parkinson's Disease: Role of Calcium-Storing Organelles and Sodium-Calcium Exchanger.

Cells. 2024-8-4

[4]
Blood-brain barrier alterations and their impact on Parkinson's disease pathogenesis and therapy.

Transl Neurodegener. 2024-7-29

[5]
The ethics of ChatGPT in medicine and healthcare: a systematic review on Large Language Models (LLMs).

NPJ Digit Med. 2024-7-8

[6]
Myricetin ameliorates cognitive impairment in 3×Tg Alzheimer's disease mice by regulating oxidative stress and tau hyperphosphorylation.

Biomed Pharmacother. 2024-8

[7]
Mechanistic Evaluation of miRNAs and Their Targeted Genes in the Pathogenesis and Therapeutics of Parkinson's Disease.

Mol Neurobiol. 2025-1

[8]
Charting new AI education in gastroenterology: Cross-sectional evaluation of ChatGPT and perplexity AI in medical residency exam.

Dig Liver Dis. 2024-8

[9]
Positron Emission Tomography Imaging of Synaptic Dysfunction in Parkinson's Disease.

Neurosci Bull. 2024-6

[10]
Metabolome subtyping reveals multi-omics characteristics and biological heterogeneity in major psychiatric disorders.

Psychiatry Res. 2023-12

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索