Busili Amani, Kumar Kanta, Kudrna Laura, Rabbani Unaib
Department of Nursing and Midwifery, Nursing College, Jazan University, Jazan, Saudi Arabia.
Department of Nursing and Midwifery, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Medicine (Baltimore). 2025 Jun 27;104(26):e43112. doi: 10.1097/MD.0000000000043112.
The coronavirus disease 2019 (COVID-19) pandemic has posed significant challenges to mental health, especially among individuals with preexisting conditions such as type 2 diabetes. The interplay between chronic physical conditions and mental health is well-documented, yet the pandemic's specific impact on the mental health of patients with type 2 diabetes remains underexplored. This study aimed to assess the prevalence of the most common mental health symptoms, including depression, anxiety, and insomnia, among type 2 diabetes patients before and during the COVID-19 pandemic to understand any potential changes in mental health outcomes.
A systematic review of 42 observational studies published between 2010 and 2022 was conducted in accordance with PRISMA guidelines. Studies were identified through 5 electronic databases and included based on predefined eligibility criteria. Two reviewers independently screened and assessed the study quality. Due to limited directly comparable data, a narrative synthesis was performed.
The review included 42 studies, with 25 (60%) scoring 6 or less out of 9 in quality assessment. The prevalence of depression among type 2 diabetes patients ranged from 5.3% to 73.6% in prepandemic studies, compared with 5.6% to 30.4% during the pandemic. Anxiety prevalence was reported between 8.4% and 65.5% before the pandemic and remained at 8.4% during the pandemic. Insomnia was prevalent in 9.6% to 48.2% of patients' prepandemic, with one study reporting a 31.4% prevalence during the pandemic. Two studies directly compared depression prevalence before and during the pandemic in the same population; one reported a significant increase from 19.3% to 30.4%, while the other found no difference.
This study suggests that while the COVID-19 pandemic did not significantly exacerbate anxiety or insomnia in patients with type 2 diabetes, there may have been an increase in depression. The findings underscore the complexity of mental health outcomes during the pandemic and highlight the need for further research to fully understand the impact of COVID-19 on the mental health of individuals with type 2 diabetes. These results suggest the importance of ongoing mental health support for this vulnerable population.
2019年冠状病毒病（COVID-19）大流行给心理健康带来了重大挑战，尤其是在患有2型糖尿病等既往疾病的个体中。慢性身体疾病与心理健康之间的相互作用已有充分记录，但大流行对2型糖尿病患者心理健康的具体影响仍未得到充分探索。本研究旨在评估2型糖尿病患者在COVID-19大流行之前和期间最常见的心理健康症状（包括抑郁、焦虑和失眠）的患病率，以了解心理健康结果的任何潜在变化。
根据PRISMA指南，对2010年至2022年发表的42项观察性研究进行了系统综述。通过5个电子数据库识别研究，并根据预先定义的纳入标准纳入研究。两名评审员独立筛选并评估研究质量。由于直接可比的数据有限，进行了叙述性综合分析。
该综述包括42项研究，其中25项（60%）在质量评估中得分为（满分9分）6分或更低。在大流行前的研究中，2型糖尿病患者的抑郁患病率在5.3%至73.6%之间，而在大流行期间为5.6%至30.4%。据报告，大流行前焦虑患病率在8.4%至65.5%之间，大流行期间保持在8.4%。在大流行前，失眠在9.6%至48.2%的患者中普遍存在，一项研究报告大流行期间患病率为31.4%。两项研究直接比较了同一人群在大流行之前和期间的抑郁患病率；一项报告从19.3%显著增加到30.4%，而另一项未发现差异。
本研究表明，虽然COVID-19大流行并未显著加剧2型糖尿病患者的焦虑或失眠，但抑郁可能有所增加。研究结果强调了大流行期间心理健康结果的复杂性，并突出了进一步研究以充分了解COVID-19对2型糖尿病患者心理健康影响的必要性。这些结果表明了对这一弱势群体持续提供心理健康支持的重要性。
