De Guzman Keshia R, Falconer Nazanin, Cottrell Neil, Coombes Ian D, Foot Holly, Koh Pei Wen, Wilkinson Shelley, Robertson Kelvin, Paradissis Chariclia, Wang William Y S, Miles Jared A, Atherton John James, Snoswell Centaine L, Bryce Vivian, Carson Sue, Jones Andrew R, Barras Michael A
Cardiology. 2025 Jun 30:1-42. doi: 10.1159/000547172.
Transition of care (ToC) is a critical time that requires effective management, especially for patients with cardiovascular disease, who have complex health needs. Pharmacists can play an integral role in improving medication safety and care coordination at ToC. This review determined the types of pharmacist-led multidisciplinary ToC services and associated outcomes in patients with cardiovascular disease.
A systematic literature search of four databases; PubMed, Embase, CINAHL, and Scopus, was undertaken from inception until June 2023. Abstracts and full text were screened against eligibility criteria. Extracted data included study characteristics, ToC service descriptions, primary and secondary outcomes, limitations, and key findings. Study findings were synthesised narratively. The types of in-patient and post-discharge activities and their effect on patient outcomes were critiqued and presented.
Of the 1822 studies identified, 37 were included in the final review. The most common primary outcome reported was 30-day all cause readmissions (n=14). Pharmacist-led ToC services incorporated a diverse combination of inpatient and post-discharge activities. The most common in-patient activities included medication history and reconciliation, patient medication education, and medication review and optimisation. The most common post-discharge activities were medication review and optimisation, adherence assessments, and medication education. Multifaceted ToC services that involved inpatient and post-discharge activities demonstrated statistically significant changes in readmission rates and other patient reported outcomes.
A variety of multifaced approaches to pharmacist-led ToC services have been evaluated within many studies, reporting favourable effects on outcomes for patients with cardiovascular disease. Tailoring ToC services to specific patient populations and settings, targeting activities to high-risk patients, and a multidisciplinary approach, are important to optimise ToC and patient outcomes.
护理过渡(ToC)是一个关键时期,需要进行有效管理,对于有复杂健康需求的心血管疾病患者而言尤为如此。药剂师在改善护理过渡期间的用药安全和护理协调方面可发挥不可或缺的作用。本综述确定了由药剂师主导的多学科护理过渡服务的类型以及心血管疾病患者的相关结局。
对四个数据库(PubMed、Embase、CINAHL和Scopus)进行了系统的文献检索,检索时间从数据库创建至2023年6月。根据纳入标准对摘要和全文进行筛选。提取的数据包括研究特征、护理过渡服务描述、主要和次要结局、局限性以及关键发现。对研究结果进行了叙述性综合分析。对住院和出院后活动的类型及其对患者结局的影响进行了评价和呈现。
在检索到的1822项研究中,最终纳入综述的有37项。报告的最常见主要结局是30天全因再入院(n = 14)。由药剂师主导的护理过渡服务包含了住院和出院后活动的多种组合。最常见的住院活动包括用药史和用药核对、患者用药教育以及用药审查与优化。最常见的出院后活动是用药审查与优化、依从性评估以及用药教育。涉及住院和出院后活动的多方面护理过渡服务在再入院率和其他患者报告结局方面显示出具有统计学意义的变化。
许多研究中评估了多种由药剂师主导的护理过渡服务的多方面方法,报告显示这些方法对心血管疾病患者的结局有积极影响。根据特定患者群体和环境量身定制护理过渡服务、针对高危患者开展活动以及采用多学科方法,对于优化护理过渡和患者结局很重要。