Fang Man, Zhang Bo, Ding Wei, Li GaoFeng
Department of Plastic and Cosmetic Surgery, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, 61 JieFangXi Road, Changsha, 410002, Hunan Province, China.
Aesthetic Plast Surg. 2025 Jun 30. doi: 10.1007/s00266-025-05020-6.
Perceived pain during local anesthesia injections in double-eyelid blepharoplasty can be influenced by both the epinephrine concentration and local anesthetics components. This study aimed to explore a new stepwise local anesthesia method for upper eyelid blepharoplasty, utilizing ropivacaine mixed with lidocaine, stepwise increase in epinephrine concentration infiltration, and stepwise specific anesthesia application during two surgical procedures.
A prospective randomized clinical trial was conducted on a cohort of patients undergoing upper double-eyelid blepharoplasty, who were randomly divided into two distinct groups: conventional local anesthesia and stepwise anesthetic method. The operative perception pain (VAS), reflexive lacrimation, postoperative periorbital appearance, and patient satisfaction were compared between the two groups.
A total of 184 patients were included and randomized. The mean visual analog scale (VAS) of the stepwise local anesthesia group was significantly lower than control (T0-T5, all P < 0.001). Meanwhile as for the probability of reflexive lacrimation, stepwise local anesthesia group was lower than control method (P < 0.01). With regard to the periorbital appearance, there are significant differences between two groups in Day 7 at ecchymosis, erythema, and swelling (P < 0.05), and the stepwise local anesthesia method group was lower than control group. However, in 1 month there are no significant differences between two groups. The satisfaction of stepwise local anesthesia group was higher than control (P = 0.016).
In summary, the stepwise local anesthesia technique employed in upper eyelid blepharoplasty demonstrates superior efficacy compared to conventional anesthesia. This technique effectively mitigates pain and immediate postoperative appearance, thereby resulting in heightened patient contentment and justifying its continued endorsement.
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双眼皮成形术中局部麻醉注射时的疼痛感受会受到肾上腺素浓度和局部麻醉药成分的影响。本研究旨在探索一种用于上睑成形术的新的分步局部麻醉方法,该方法使用罗哌卡因与利多卡因混合,在两个手术步骤中逐步增加肾上腺素浓度进行浸润,并逐步进行特定麻醉应用。
对一组接受上睑双眼皮成形术的患者进行前瞻性随机临床试验,将其随机分为两组:传统局部麻醉组和分步麻醉法组。比较两组的手术感知疼痛(视觉模拟评分法[VAS])、反射性流泪、术后眶周外观及患者满意度。
共纳入184例患者并进行随机分组。分步局部麻醉组的平均视觉模拟评分(VAS)显著低于对照组(T0 - T5,所有P < 0.001)。同时,就反射性流泪的发生率而言,分步局部麻醉组低于对照方法(P < 0.01)。关于眶周外观,两组在术后第7天的瘀斑、红斑和肿胀方面存在显著差异(P < 0.05),且分步局部麻醉法组低于对照组。然而,在1个月时两组之间无显著差异。分步局部麻醉组的满意度高于对照组(P = 0.016)。
总之,上睑成形术中采用的分步局部麻醉技术与传统麻醉相比显示出更好的疗效。该技术有效减轻了疼痛和术后即刻外观问题,从而提高了患者满意度,证明其值得继续推广。
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