Balmain Bryce N, Schultz Martin G, Morris Norman R, Shiino Kenji, Sabapathy Surendran
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital, 7232 Greenville Ave, Dallas, TX, 75231, USA.
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Eur J Appl Physiol. 2025 Jun 30. doi: 10.1007/s00421-025-05862-7.
Central blood pressure can be estimated non-invasively using radial applanation tonometry. However, the stability and accuracy of applanation tonometry signals is operator-dependent. We examined the concordance between finger and radial artery pressure waveforms captured using an automated, beat-by-beat, photoplethysmograph device (Finometer PRO) and radial applanation tonometry respectively, to estimate central pressure waveform characteristics including systolic (SP), diastolic (DP), augmented (AP), reservoir (RP), and excess (XSP) pressure at rest and during a period of elevated and sustained arterial blood pressure. The central pressure waveform characteristics were estimated from finger artery pressure waveforms captured by the Finometer, and were compared to those derived from radial artery pressure waveforms captured using applanation tonometry at baseline (Rest) and during a brief period of circulatory occlusion (OCC) immediately following an isometric handgrip exercise challenge (performed at 40% maximal voluntary contraction) in 24 healthy men (25 ± 5 years). Central pressure waveform parameters derived from the Finometer device were not different to those estimated from radial applanation tonometry: SP (Rest: 3 ± 2; OCC: 4 ± 2 mmHg), DP (Rest: 1 ± 1; OCC 1 ± 2 mmHg), AP (Rest:2 ± 3; OCC: 3 ± 3 mmHg), RP (Rest: 3 ± 4; OCC: 3 ± 5 mmHg), and XSP (Rest: 2 ± 2; OCC: 2 ± 3 mmHg) (all p > 0.05). Furthermore, intra-class correlation coefficients between methods were uniformly high for the estimated change from Rest-to-OCC in all parameters: SP (r = 0.97), DP (r = 0.96), AP (r = 0.94), RP (r = 0.95), and XSP (Rest: r = 0.98) (all p < 0.01). These findings demonstrate that the Finometer device may serve as an alternative automated device to radial applanation tonometry for capturing peripheral pressure waveforms that allow similar estimation of central pressure waveform characteristics.
可使用桡动脉压平式眼压计无创估计中心血压。然而，压平式眼压计信号的稳定性和准确性取决于操作人员。我们分别使用自动逐搏光电容积脉搏波描记装置（Finometer PRO）和桡动脉压平式眼压计，检测静息状态以及动脉血压升高并持续期间所采集的手指和桡动脉压力波形之间的一致性，以估计中心压力波形特征，包括收缩压（SP）、舒张压（DP）、增强压（AP）、弹性腔压力（RP）和过冲压（XSP）。中心压力波形特征由Finometer采集的手指动脉压力波形估计得出，并与24名健康男性（25±5岁）在基线（静息）和等长握力运动挑战（以最大自主收缩力的40%进行）后立即进行的短暂循环阻断（OCC）期间，使用压平式眼压计采集的桡动脉压力波形得出的特征进行比较。Finometer装置得出的中心压力波形参数与压平式眼压计估计的参数无差异：SP（静息：3±2；OCC：4±2 mmHg），DP（静息：1±1；OCC 1±2 mmHg），AP（静息：2±3；OCC：3±3 mmHg），RP（静息：3±4；OCC：3±5 mmHg），以及XSP（静息：2±2；OCC：2±3 mmHg）（所有p>0.05）。此外，在所有参数中，从静息到OCC的估计变化，两种方法之间的组内相关系数均较高：SP（r = 0.97），DP（r = 0.96），AP（r = 0.94），RP（r = 0.95），以及XSP（静息：r = 0.98）（所有p<0.01）。这些发现表明，Finometer装置可作为桡动脉压平式眼压计的替代自动化设备，用于采集外周压力波形，从而对中心压力波形特征进行类似的估计。
