Zheng Daniel J, Rodday Angie Mae, Castellino Sharon M, Renfro Lindsay A, Lerner Debra, Henderson Tara O, Wu Yue, Kelly Kara M, Conti Rena M, Parsons Susan K
Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts, USA.
Pediatr Blood Cancer. 2025 Sep;72(9):e31841. doi: 10.1002/pbc.31841. Epub 2025 Jun 30.
Caregiver work productivity loss is an important spillover in estimating the costs of pediatric cancer diagnosis and treatment. In this prospective multi-institutional study, cross-sectional analysis of 155 caregivers of children with high-risk Hodgkin lymphoma revealed 9% at-work productivity loss in the four weeks leading up to diagnosis including interference in all four domains measured by the Caregiver Work Limitations Questionnaire: time management, physical tasks, mental-interpersonal tasks, and output tasks. The degree of productivity loss experienced by these caregivers at diagnosis is substantial. Longitudinal analysis of caregiver burden throughout treatment is needed to understand the full extent of the economic impact.
照顾者工作效率损失是估算儿童癌症诊断和治疗成本时的一项重要溢出效应。在这项前瞻性多机构研究中，对155名高危霍奇金淋巴瘤患儿的照顾者进行的横断面分析显示，在诊断前四周，其工作效率损失达9%，包括照顾者工作限制问卷所衡量的所有四个领域受到干扰：时间管理、体力任务、心理人际任务和产出任务。这些照顾者在诊断时所经历的工作效率损失程度相当大。需要对整个治疗过程中的照顾者负担进行纵向分析，以全面了解经济影响。
