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灌注压力传感器对使用眼睑撑开器的猪眼模型中后囊膜抬高的影响。

Effect of perfusion pressure sensors on posterior capsule elevation in the porcine eye model with eyelid speculums.

作者信息

Suzuki Hisaharu

机构信息

Zengyo Suzuki Eye Clinic, Kanagawa, Japan.

出版信息

Sci Rep. 2025 Jul 1;15(1):21908. doi: 10.1038/s41598-025-08134-8.

DOI:10.1038/s41598-025-08134-8
PMID:40593095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12219668/
Abstract

This study evaluated the posterior capsule elevation ratio after occlusion break in a porcine eye model with an eyelid speculum (ES) using Centurion Vision System with Active Sentry handpiece (AS). The mean intraocular pressure of the porcine eyes with the ES was significantly higher than that of without the ES (15.42 ± 4.10 mmHg vs. 21.86 ± 4.12 mmHg, P = 0.0003). Changes in the posterior capsule elevation were observed using the slit side view method in the following four groups: with an ES using AS [AS (ES+)], without an ES using AS [AS (ES-)], with an ES using the Ozil handpiece [OZ (ES+)], and without an ES using OZ [OZ (ES-)]. Eleven eyes in each group were tested. AS (ES+) and OZ (ES+) had a significantly higher rate of posterior capsule elevation than did AS (ES-) and OZ (ES-) (P = 0.0135 and P = 0.010). AS (ES+) and AS (ES-) significantly suppressed posterior capsule elevation compared with OZ (ES+) and OZ (ES-) (P = 0.034 and P = 0.045). Porcine eyes with ES had increased IOP and greater posterior capsule elevation after occlusion break than did those without. AS effectively suppressed posterior capsule elevation better than did OZ.

摘要

本研究使用配备主动哨兵手持件（AS）的Centurion视觉系统，在带有眼睑撑开器（ES）的猪眼模型中评估了闭塞中断后的后囊膜抬高率。使用ES的猪眼平均眼压显著高于未使用ES的猪眼（15.42±4.10 mmHg对21.86±4.12 mmHg，P = 0.0003）。采用裂隙侧视法观察了以下四组后囊膜抬高的变化：使用AS且带有ES [AS（ES +）]、使用AS且不带有ES [AS（ES -）]、使用奥兹手持件且带有ES [OZ（ES +）]、使用奥兹且不带有ES [OZ（ES -）]。每组测试11只眼。AS（ES +）和OZ（ES +）的后囊膜抬高率显著高于AS（ES -）和OZ（ES -）（P = 0.0135和P = 0.010）。与OZ（ES +）和OZ（ES -）相比，AS（ES +）和AS（ES -）显著抑制了后囊膜抬高（P = 0.034和P = 0.045）。与没有ES的猪眼相比，带有ES的猪眼在闭塞中断后眼压升高且后囊膜抬高更明显。与OZ相比，AS能更有效地抑制后囊膜抬高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/76c2b294195d/41598_2025_8134_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/1f7b907fc859/41598_2025_8134_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/3de9e88f2a60/41598_2025_8134_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/b7ccf7d1d672/41598_2025_8134_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/670713719def/41598_2025_8134_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/76c2b294195d/41598_2025_8134_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/1f7b907fc859/41598_2025_8134_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/3de9e88f2a60/41598_2025_8134_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/b7ccf7d1d672/41598_2025_8134_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/670713719def/41598_2025_8134_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8d/12219668/76c2b294195d/41598_2025_8134_Fig5_HTML.jpg

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本文引用的文献

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Vitreous-lens interface changes after cataract surgery using active fluidics and active sentry with high and low infusion pressure settings.白内障手术后采用主动流控和主动哨兵技术，在高、低灌注压力设置下的玻璃体-晶状体界面变化。
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Effect of elevated irrigation bottle height during cataract surgery on corneal endothelial cells in porcine eyes.白内障手术中升高冲洗瓶高度对猪眼角膜内皮细胞的影响。
BMC Ophthalmol. 2023 May 11;23(1):211. doi: 10.1186/s12886-023-02954-w.
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