Foster Megan, Hudson Kelsey, Ehrig Jessica C, Sharpe Emily E, Hofkamp Michael P
Texas A&M University College of Medicine, Round Rock, TX, USA.
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Baylor Scott & White Medical Center-Temple, Temple, TX, USA.
Can J Anaesth. 2025 Jul 1. doi: 10.1007/s12630-025-03004-3.
We aimed to identify the neuraxial anesthesia failure rate of de novo single-injection spinal and combined spinal-epidural anesthesia for postpartum tubal ligation at our hospital along with variables associated with neuraxial anesthesia failure.
We conducted a single-centre retrospective cohort study of patients who underwent a postpartum tubal ligation with de novo single-injection spinal or combined spinal-epidural anesthesia from 1 January 2020 to 31 December 2022 at Baylor Scott & White Medical Center-Temple (Temple, TX, USA). We defined neuraxial anesthesia failure as conversion to general anesthesia involving the use of an endotracheal tube or supraglottic airway, administration of intravenous propofol at doses > 10 mg, intravenous fentanyl > 100 µg, or the use of inhaled nitrous oxide.
During the study period, 243 patients underwent postpartum tubal ligation with single-injection spinal or combined spinal-epidural anesthesia, and 28 (11.5%) had neuraxial anesthesia failure. Using a multivariate logistic regression designed to predict neuraxial anesthesia failure using variables of interest, we found that a 5-min increase in time from spinal anesthesia placement to skin incision was associated with neuraxial anesthetic failure (adjusted odds ratio [aOR], 3.10; 95% confidence interval [CI], 2.01 to 4.79; P < 0.001) along with a 5-min increase in time from skin incision to wound closure (aOR 1.35; 95% CI, 1.10 to 1.66; P = 0.004) CONCLUSION: Patients who underwent postpartum tubal ligation under single-injection spinal or combined spinal epidural anesthesia had a neuraxial failure rate of 11.5%. Time from spinal placement to skin incision and time from skin incision to wound closure were independently associated with neuraxial anesthesia failure.
我们旨在确定我院首次单次注射脊髓麻醉和腰麻-硬膜外联合麻醉用于产后输卵管结扎的神经轴麻醉失败率以及与神经轴麻醉失败相关的变量。
我们对2020年1月1日至2022年12月31日在美国德克萨斯州坦普尔贝勒·斯科特与怀特医疗中心接受首次单次注射脊髓麻醉或腰麻-硬膜外联合麻醉进行产后输卵管结扎的患者进行了一项单中心回顾性队列研究。我们将神经轴麻醉失败定义为转为全身麻醉,包括使用气管内导管或声门上气道、静脉注射丙泊酚剂量>10mg、静脉注射芬太尼>100μg或使用吸入氧化亚氮。
在研究期间,243例患者接受了单次注射脊髓麻醉或腰麻-硬膜外联合麻醉进行产后输卵管结扎,其中28例(11.5%)出现神经轴麻醉失败。使用多因素逻辑回归分析,以感兴趣的变量预测神经轴麻醉失败,我们发现从脊髓麻醉置管到皮肤切开时间增加5分钟与神经轴麻醉失败相关(调整后的优势比[aOR],3.10;95%置信区间[CI],2.01至4.79;P<0.001),同时从皮肤切开到伤口缝合时间增加5分钟也相关(aOR 1.35;95%CI,1.10至1.66;P=0.004)。结论:接受单次注射脊髓麻醉或腰麻-硬膜外联合麻醉进行产后输卵管结扎的患者神经轴麻醉失败率为11.5%。从脊髓置管到皮肤切开的时间以及从皮肤切开到伤口缝合的时间与神经轴麻醉失败独立相关。