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中国南方某急诊科中华眼镜蛇咬伤临床及流行病学特征的回顾性分析

Retrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency department.

作者信息

Huang Zhou, Lv Xiao-Dan, Huang Dong-Ling, Wang Fan, Wei Wan-Xia, Pang Guo-Dong, Wang Wei

机构信息

Department of Emergency, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.

出版信息

Sci Rep. 2025 Jul 1;15(1):21960. doi: 10.1038/s41598-025-04204-z.

Abstract

In China, it is estimated that over 100,000 snakebite incidents occur each year, significantly endangering human life. This study retrospectively analyzed the treatment data of Chinese cobra bite patients in a Chinese hospital from 2010 to July 2017. It was found that local necrosis typically occurs after a Chinese cobra bite, and effective treatment involves removal of the necrotic tissue and facilitating wound healing with anti-infection measures. The extent of local damage after the bite was correlated with creatine kinase levels. In addition, early administration of Chinese cobra antivenom was beneficial as it alleviated local necrosis and reduced the likelihood of adverse complications. However, under the current treatment protocols, the use or nonuse of Chinese cobra antivenom does not significantly impact survival outcomes.

摘要

在中国,据估计每年发生超过10万起蛇咬伤事件,严重危及人类生命。本研究回顾性分析了2010年至2017年7月间一家中国医院收治的中华眼镜蛇咬伤患者的治疗数据。研究发现,中华眼镜蛇咬伤后通常会出现局部坏死,有效的治疗包括清除坏死组织并采取抗感染措施促进伤口愈合。咬伤后局部损伤的程度与肌酸激酶水平相关。此外,早期使用中华眼镜蛇抗蛇毒血清有益,因为它可减轻局部坏死并降低不良并发症的发生可能性。然而,按照目前的治疗方案,使用或不使用中华眼镜蛇抗蛇毒血清对生存结果并无显著影响。

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