Kim Yaelim, Choi Yeonghun, Lee Kyu-Na, Sang Hyunji, Han Kyungdo, Kim Sunyoung, Rhee Sang Youl
Department of Medicine, Kyung Hee University, Seoul, Korea.
Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Seoul, Korea.
Sci Rep. 2025 Jul 1;15(1):21185. doi: 10.1038/s41598-025-04193-z.
This study analyzed the prevalence of metabolic syndrome (MetS) among Korean adults aged 19 and older over the past 15 years. A cross-sectional study of data from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2007 to 2022 was conducted. The study included 87,397 subjects. MetS was defined according to the National Cholesterol Education Program-Third Adult Treatment Panel (NCEP-ATP) III and the Korean Society for the Study of Obesity (KOSSO) criteria. MetS prevalence increased from 22.8% in 2007 to 28.6% in 2022 but showed sex differences, with males increasing (24.5% to 36.8%) and females decreasing (20.6% to 19.5%). Among the components of MetS, hyperglycemia and abdominal obesity showed the most significant increases (1.51-fold and 1.29-fold, respectively). While hyperglycemia increased across all age groups in both sexes, abdominal obesity increased most in males aged 30-39 (1.98-fold) and 19-29 (1.81-fold). Low high-density lipoprotein cholesterol (HDL-C) was the only component that decreased (0.62-fold) and was more prevalent among females. In the sub-analysis of those aged 65 and older, MetS increased in both males and females but was more prevalent in females. Individuals with MetS had higher rates of current smoking, heavy drinking, physical inactivity, and carbohydrate consumption. The prevalence of MetS is gradually increasing in Korea, and hyperglycemia and abdominal obesity are rapidly increasing, especially in younger males. Although the prevalence of MetS in females is decreasing due to changes in the social environment, continuous efforts are needed for postmenopausal females. Targeted health policies and interventions should be established.
本研究分析了过去15年中19岁及以上韩国成年人代谢综合征（MetS）的患病率。对2007年至2022年韩国国家健康与营养检查调查（KNHANES）的数据进行了横断面研究。该研究纳入了87397名受试者。MetS根据美国国家胆固醇教育计划成人治疗专家组第三次报告（NCEP-ATP）III和韩国肥胖研究学会（KOSSO）的标准进行定义。MetS患病率从2007年的22.8%上升至2022年的28.6%，但存在性别差异，男性患病率上升（从24.5%升至36.8%），女性患病率下降（从20.6%降至19.5%）。在MetS的各组成部分中，高血糖和腹型肥胖的增幅最为显著（分别为1.51倍和1.29倍）。虽然高血糖在所有年龄组的男性和女性中均有所上升，但腹型肥胖在30-39岁男性（1.98倍）和19-29岁男性（1.81倍）中增幅最大。低高密度脂蛋白胆固醇（HDL-C）是唯一下降的组成部分（0.62倍），且在女性中更为普遍。在65岁及以上人群的亚组分析中，男性和女性的MetS患病率均有所上升，但女性更为普遍。患有MetS的个体当前吸烟、大量饮酒、缺乏身体活动和碳水化合物摄入量较高的比例更高。韩国MetS的患病率正在逐渐上升，高血糖和腹型肥胖迅速增加，尤其是在年轻男性中。尽管由于社会环境的变化，女性MetS的患病率正在下降，但绝经后女性仍需要持续努力。应制定有针对性的健康政策和干预措施。
