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不同形状组织扩张器对猪腔内压力、氧张力、组织病理学变化及皮肤扩张的影响

Effects of different-shaped tissue expanders on transluminal pressure, oxygen tension, histopathologic changes, and skin expansion in pigs.

作者信息

Brobmann G F, Huber J

出版信息

Plast Reconstr Surg. 1985 Nov;76(5):731-6. doi: 10.1097/00006534-198511000-00013.

DOI:10.1097/00006534-198511000-00013
PMID:4059413
Abstract

This study, performed on domestic pigs, was designed to show whether the shape and size of a tissue expander influences the amount of surface area increase. When a defect is irregular, a larger custom-fitted implant is more efficient than several smaller expanders. Oval implants gained 5 percent more skin using 50 percent less time and almost 20 percent less intraluminal pressure, while U-shaped implants yield 2.2 percent more skin in 10 percent less time with 35 to 50 percent less pressure when compared with several smaller implants covering the same surface area. Transcutaneous TpO2 measurements and histologic evaluation revealed no significant difference between all implant shapes. These results show that less time, pressure, and volume are needed in a larger implant to gain the same surface area as would be attained from several smaller implants, thus sparing the patient more discomfort, trauma, and risk of infection by reducing the number of filling domes and hence the number of fillings.

摘要

这项针对家猪开展的研究旨在表明组织扩张器的形状和大小是否会影响表面积增加量。当缺损不规则时,定制的较大植入物比几个较小的扩张器更有效。椭圆形植入物在使用时间减少50%、腔内压力降低近20%的情况下,获得的皮肤增加了5%;与覆盖相同表面积的几个较小植入物相比,U形植入物在时间减少10%、压力降低35%至50%的情况下,产生的皮肤增加了2.2%。经皮TpO2测量和组织学评估显示,所有植入物形状之间无显著差异。这些结果表明,较大的植入物获得与几个较小植入物相同表面积所需的时间、压力和体积更少,从而通过减少填充球囊数量进而减少填充次数,使患者免受更多不适、创伤和感染风险。

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