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[蛋白质 - 热量营养不良中的细胞免疫]

[Cellular immunity in protein-caloric malnutrition].

作者信息

Khadraoui S, Lopez V, Hamza B, Smith N J

出版信息

Arch Fr Pediatr. 1977 Feb;34(2):143-53.

PMID:405954
Abstract

In order to have a clearer idea on the relationship between infectious diseases and malnutrition, cellular immunity is studied in 3 to 18 months old malnourished and healthy infants. Nutritional status is evaluated by the food intake the anthropologic measurements and some biological parameters like transferrin. Cellular immunity is investigated by skin tests to tuberculin, monilia, P.H.A. and DNCB. Absolute number of peripheral lymphocytes and percentage of T cells are studied too. The results show that there is a cellular immunity deficiency: frequent non-response to antigens, weak sensitization to DNCB. Some patients have a low percentage of spontaneous rosettes. The transferrin titering is useful to appreciate the nutritional status and the iron therapy opportunity, the prognostic and the immunitary possibilities.

摘要

为了更清楚地了解传染病与营养不良之间的关系,对3至18个月大的营养不良和健康婴儿的细胞免疫进行了研究。通过食物摄入量、人体测量以及一些生物学参数(如转铁蛋白)来评估营养状况。通过结核菌素、念珠菌、PHA和DNCB皮肤试验来研究细胞免疫。还研究了外周淋巴细胞的绝对数量和T细胞百分比。结果表明存在细胞免疫缺陷:对抗原频繁无反应,对DNCB致敏性弱。一些患者自发玫瑰花结百分比低。转铁蛋白滴定有助于评估营养状况、铁治疗时机、预后和免疫可能性。

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