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比较老年腹部或盆腔手术患者中降低体温过低和寒战的升温策略:一项网状Meta分析。

Comparing warming strategies to reduce hypothermia and shivering in elderly abdominal or pelvic surgery patients: a network meta-analysis.

作者信息

Zheng Wenyun, Huang Bin, Bao Li, Wang Jun, Jin Jingfen

机构信息

Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, China.

Department of Lung Transplantation, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, China.

出版信息

Sci Rep. 2025 Jul 1;15(1):22356. doi: 10.1038/s41598-025-04644-7.

Abstract

Perioperative hypothermia (PHT) and shivering represent significant clinical challenges in geriatric surgical populations. This network meta-analysis (NMA) systematically evaluates the comparative efficacy of various warming interventions in preventing PHT and shivering among elderly patients undergoing abdominal or pelvic surgery. We conducted a comprehensive literature search across PubMed, EMBASE, Cochrane library, and China Wanfang databases for randomized controlled trials (RCTs) published up to April 2024. Inclusion criteria encompassed RCTs comparing warming strategies in patients aged ≥ 60 years undergoing abdominal or pelvic surgery. Methodological quality was assessed using the Cochrane Risk of Bias tool 2.0. Primary outcomes included incidence rates of PHT and shivering. A frequentist approach to NMA was performed using random-effects models, with surface under the cumulative ranking curve (SUCRA) values calculated for treatment ranking. The analysis incorporated 18 RCTs (n = 2161) evaluating eight distinct warming strategies. Network meta-analysis revealed that forced-air warming with blankets at ≥ 40 °C (FABWH) demonstrated superior efficacy for PHT prevention, while forced-air warming at ≥ 40 °C (FAWH) showed optimal performance for shivering reduction. Compared to standard care, FABWH significantly reduced PHT risk (RR = 0.14, 95% CI 0.04-0.46; P = 0.0012) and shivering incidence (RR = 0.21, 95% CI 0.07-0.69; P = 0.008). FAWH exhibited comparable effectiveness, with risk reductions of 72% for PHT (RR = 0.28, 95% CI 0.13-0.58; P = 0.0006) and 84% for shivering (RR = 0.16, 95% CI 0.07-0.39; P < 0.001). This NMA provides robust evidence that active warming strategies, particularly FABWH and FAWH, significantly mitigate PHT and shivering risks in elderly surgical patients. Future research should focus on long-term outcomes and cost-effectiveness analyses to optimize clinical decision-making.

摘要

围手术期低温(PHT)和寒战是老年外科患者面临的重大临床挑战。这项网状Meta分析(NMA)系统地评估了各种保暖干预措施在预防接受腹部或盆腔手术的老年患者发生PHT和寒战方面的相对疗效。我们对PubMed、EMBASE、Cochrane图书馆和中国万方数据库进行了全面的文献检索,以查找截至2024年4月发表的随机对照试验(RCT)。纳入标准包括比较年龄≥60岁接受腹部或盆腔手术患者的保暖策略的RCT。使用Cochrane偏倚风险工具2.0评估方法学质量。主要结局包括PHT和寒战的发生率。使用随机效应模型进行NMA的频率学派方法,并计算累积排序曲线下面积(SUCRA)值以进行治疗排序。该分析纳入了18项RCT(n = 2161),评估了8种不同的保暖策略。网状Meta分析显示,≥40°C的带毯强制空气加温(FABWH)在预防PHT方面显示出更好的疗效,而≥40°C的强制空气加温(FAWH)在减少寒战方面表现最佳。与标准护理相比,FABWH显著降低了PHT风险(RR = 0.14,95% CI 0.04 - 0.46;P = 0.0012)和寒战发生率(RR = 0.21,95% CI 0.07 - 0.69;P = 0.008)。FAWH表现出相当的效果,PHT风险降低72%(RR = 0.28,95% CI 0.13 - 0.58;P = 0.0006),寒战风险降低84%(RR = 0.16,95% CI 0.07 - 0.39;P < 0.001)。这项NMA提供了有力证据,表明主动保暖策略,特别是FABWH和FAWH,可显著降低老年手术患者的PHT和寒战风险。未来的研究应关注长期结局和成本效益分析,以优化临床决策。

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