Ullah Sifat, Javed Ali, Aljasem Muteb, Saudagar Abdul Khader Jilani
Department of Software Engineering, University of Engineering and Technology-Taxila, Taxila, 47050, Pakistan.
Department of Robotics, Electronics, and Computer Engineering, Bowling Green State University, Bowling Green, OH, USA.
BMC Med Imaging. 2025 Jul 1;25(1):257. doi: 10.1186/s12880-025-01785-z.
Chronic wounds have emerged as a significant medical challenge due to their adverse effects, including infections leading to amputations. Over the past few years, the prevalence of chronic wounds has grown, thus posing significant health hazards. It is now becoming necessary to automate the wound assessment mechanism to limit the dependence of healthcare practitioners on manual methods. Therefore, a need exists for developing an effective wound classifier that enables practitioners to classify wounds quickly and reliably. This work proposed Eff-ReLU-Net, an improved EfficientNet-B0-based deep learning model for accurately identifying multiple categories of wounds. More precisely, we introduced the ReLU activation function over the Swish in our Eff-ReLU-Net because of its simplicity, reliability, and efficiency. Additionally, we introduced three fully connected dense layers at the end to reliably capture more distinct features, leading to improved multi-class wound classification. We also employed augmentation approaches such as fixed-angle rotations at 90°, 180°, and 270°, rotational invariance, random rotation, and translation to improve data diversity and samples for better model generalization and combating overfitting. The proposed model's effectiveness is assessed utilizing the publicly available AZH and Medetec wound datasets. We also conducted the cross-corpora evaluation to show the generalizability of our method. The proposed model achieved an accuracy, precision, recall, and F1-score of 92.33%, 97.66%, 95.33%, and 96.48% on Medetec, respectively. However, for the AZH dataset, the attained accuracy, precision, recall, and F1-score are 90%, 89.45%, 92,19%, and 90.84%, respectively. These results validate the effectiveness of our proposed Eff-ReLU-Net method for classifying chronic wounds.
慢性伤口因其不良影响,包括导致截肢的感染,已成为一项重大的医学挑战。在过去几年中,慢性伤口的患病率不断上升,从而带来了重大的健康危害。现在有必要使伤口评估机制自动化,以减少医疗从业者对手动方法的依赖。因此,需要开发一种有效的伤口分类器,使从业者能够快速、可靠地对伤口进行分类。这项工作提出了Eff-ReLU-Net,这是一种基于EfficientNet-B0改进的深度学习模型,用于准确识别多种类型的伤口。更确切地说,我们在Eff-ReLU-Net中用ReLU激活函数取代了Swish,因为它简单、可靠且高效。此外,我们在末尾引入了三个全连接密集层,以可靠地捕获更多不同特征,从而改进多类伤口分类。我们还采用了增强方法,如90°、180°和270°的固定角度旋转、旋转不变性、随机旋转和平移,以提高数据多样性和样本数量,从而实现更好的模型泛化并对抗过拟合。利用公开可用的AZH和Medetec伤口数据集评估了所提出模型的有效性。我们还进行了跨语料库评估,以展示我们方法的通用性。所提出的模型在Medetec数据集上的准确率、精确率、召回率和F1分数分别达到了92.33%、97.66%、95.33%和96.48%。然而,对于AZH数据集,所达到的准确率、精确率、召回率和F1分数分别为90%、89.45%、92.19%和90.84%。这些结果验证了我们提出的Eff-ReLU-Net方法对慢性伤口进行分类的有效性。