• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新发传染病的感染预防与控制措施:中国首例输入性拉沙热病例的经验教训

Infection prevention and control measures for emerging infectious disease: lessons learned from the first case of imported Lassa fever in China.

作者信息

Peng Yalan, Wang Yantong, Li Shiyu, Huang Jing, Shi Wu, Luo Ruocheng, Pan Xianmou, Huang Wenzhi, Qiao Fu, Chen Yi

机构信息

Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.

Department of Infection Control, West China Hospital, Sichuan University, Chengdu, 610041, China.

出版信息

Antimicrob Resist Infect Control. 2025 Jul 1;14(1):74. doi: 10.1186/s13756-025-01597-4.

DOI:10.1186/s13756-025-01597-4
PMID:40598396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12210627/
Abstract

BACKGROUND

Lassa fever is an acute viral hemorrhagic disease prevalent in West Africa. West China Hospital of Sichuan University (WCHSCU) received China's first imported case of Lassa fever from overseas. We described the epidemiological investigation and infection prevention and control measures of this case following the confirmed diagnosis.

METHODS

An emergency epidemiological team defined close contacts and implemented infection prevention and control (IPC) measures: (1) isolation in a designated isolation room, (2) environmental disinfection for high-, medium-, and low-risk areas, (3) 21-day quarantine for contacts. Data were collected via field observations and medical records.

RESULTS

We identified 6 close contacts and 74 general contacts, who were subsequently quarantined for 21 days. The hospital environment was classified into high, medium, and low-risk areas, and corresponding cleaning and disinfection measures were implemented. Ultimately, no new infection cases emerged.

CONCLUSION

Rapid risk stratification, strict isolation protocols, and multidisciplinary coordination effectively prevented transmission, underscoring the importance of preparedness in non-endemic regions.

摘要

背景

拉沙热是一种在西非流行的急性病毒性出血热疾病。四川大学华西医院接收了中国首例境外输入性拉沙热病例。确诊后,我们描述了该病例的流行病学调查及感染预防与控制措施。

方法

一支应急流行病学团队确定了密切接触者并实施感染预防与控制(IPC)措施:(1)在指定隔离病房隔离,(2)对高、中、低风险区域进行环境消毒,(3)对接触者进行21天隔离观察。通过现场观察和病历收集数据。

结果

我们确定了6名密切接触者和74名一般接触者,随后对他们进行了21天隔离观察。医院环境被划分为高、中、低风险区域,并实施了相应的清洁和消毒措施。最终,未出现新的感染病例。

结论

快速的风险分层、严格的隔离方案以及多学科协作有效地预防了传播,凸显了非流行地区做好准备工作的重要性。

相似文献

1
Infection prevention and control measures for emerging infectious disease: lessons learned from the first case of imported Lassa fever in China.新发传染病的感染预防与控制措施:中国首例输入性拉沙热病例的经验教训
Antimicrob Resist Infect Control. 2025 Jul 1;14(1):74. doi: 10.1186/s13756-025-01597-4.
2
Drivers of Lassa fever in an endemic area of southwestern Nigeria (2017-2021): An epidemiological study.尼日利亚西南部一个地方病流行区拉沙热的驱动因素(2017 - 2021年):一项流行病学研究。
PLoS One. 2025 Jun 25;20(6):e0327143. doi: 10.1371/journal.pone.0327143. eCollection 2025.
3
Efficiency evaluation on case finding strategy for COVID-19 outbreak control under China's "dynamic zero-case policy": a retrospective field epidemiology study.中国“动态清零”政策下新冠疫情防控病例发现策略的效率评估:一项回顾性现场流行病学研究
Front Public Health. 2025 Jun 13;13:1516208. doi: 10.3389/fpubh.2025.1516208. eCollection 2025.
4
The epidemiology of Lassa fever in Ghana: a study on the 2023 Lassa fever outbreak in Ghana.加纳拉沙热的流行病学:关于2023年加纳拉沙热疫情的研究
Front Public Health. 2025 Apr 28;13:1542842. doi: 10.3389/fpubh.2025.1542842. eCollection 2025.
5
Measures implemented in the school setting to contain the COVID-19 pandemic.学校为控制 COVID-19 疫情而采取的措施。
Cochrane Database Syst Rev. 2022 Jan 17;1(1):CD015029. doi: 10.1002/14651858.CD015029.
6
Epidemiological characteristics and hospital outcomes of hospitalized Lassa fever cases during the 2022-2023 outbreak in Liberia.2022 - 2023年利比里亚爆发期间住院拉沙热病例的流行病学特征及医院治疗结果
F1000Res. 2025 May 15;13:661. doi: 10.12688/f1000research.150743.2. eCollection 2024.
7
Impact of imported COVID-19 cases on South Korea's response: variant transitions and regional patterns (2020-2023).输入性新冠病例对韩国应对措施的影响:变异株演变与区域模式(2020 - 2023年)
BMC Infect Dis. 2025 Jul 1;25(1):820. doi: 10.1186/s12879-025-11260-3.
8
Physical interventions to interrupt or reduce the spread of respiratory viruses.物理干预措施以阻断或减少呼吸道病毒的传播。
Cochrane Database Syst Rev. 2023 Jan 30;1(1):CD006207. doi: 10.1002/14651858.CD006207.pub6.
9
Control measures following a case of imported Lassa fever from Togo, North Rhine Westphalia, Germany, 2016.2016年德国北莱茵-威斯特法伦州多哥输入性拉沙热病例后的防控措施
Euro Surveill. 2017 Sep;22(39). doi: 10.2807/1560-7917.ES.2017.22.39.17-00088.
10
Risk factors for the spread of African Swine Fever in China: A systematic review of Chinese-language literature.中国非洲猪瘟传播的风险因素:对中文文献的系统回顾。
Transbound Emerg Dis. 2022 Sep;69(5):e1289-e1298. doi: 10.1111/tbed.14573. Epub 2022 May 11.

本文引用的文献

1
Digitalizing disease surveillance: experience from Sierra Leone.疾病监测数字化:来自塞拉利昂的经验
Health Policy Plan. 2025 Jan 11;40(1):85-96. doi: 10.1093/heapol/czae039.
2
The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory-Crimean Congo Haemorrhagic Fever Virus and Lassa Virus.生物安全研究路线图:寻找支持实验室操作的证据——克里米亚-刚果出血热病毒和拉沙病毒
Appl Biosaf. 2023 Dec 1;28(4):216-229. doi: 10.1089/apb.2022.0044. Epub 2023 Dec 5.
3
Predictors of Lassa fever diagnosis in suspected cases reporting to health facilities in Nigeria.
尼日利亚医疗机构上报疑似拉沙热病例的诊断预测因子。
Sci Rep. 2023 Apr 21;13(1):6545. doi: 10.1038/s41598-023-33187-y.
4
After action review of the response to an outbreak of Lassa fever in Sierra Leone, 2019: Best practices and lessons learnt.2019 年塞拉利昂爆发拉萨热疫情后的应对行动回顾:最佳实践和经验教训。
PLoS Negl Trop Dis. 2022 Oct 5;16(10):e0010755. doi: 10.1371/journal.pntd.0010755. eCollection 2022 Oct.
5
Beyond Lassa Fever: Systemic and structural barriers to disease detection and response in Sierra Leone.超越拉沙热:塞拉利昂疾病检测和应对的系统和结构障碍。
PLoS Negl Trop Dis. 2022 May 19;16(5):e0010423. doi: 10.1371/journal.pntd.0010423. eCollection 2022 May.
6
Lassa Fever: Epidemiology, Clinical Features, Diagnosis, Management and Prevention.拉沙热:流行病学、临床特征、诊断、治疗和预防。
Infect Dis Clin North Am. 2019 Dec;33(4):933-951. doi: 10.1016/j.idc.2019.08.002.
7
Lassa fever: With 50 years of study, hundreds of thousands of patients and an extremely high disease burden, what have we learned?拉沙热:经过50年的研究、数十万患者以及极其沉重的疾病负担,我们学到了什么?
Curr Opin Virol. 2019 Aug;37:123-131. doi: 10.1016/j.coviro.2019.07.009. Epub 2019 Aug 31.
8
Lesson learned from the investigation and response of Lassa fever outbreak, Margibi County, Liberia, 2018: case report.从 2018 年利比里亚马吉比县拉沙热疫情的调查和应对中吸取的教训:病例报告。
BMC Infect Dis. 2019 Jul 11;19(1):610. doi: 10.1186/s12879-019-4257-z.
9
A cluster of nosocomial Lassa fever cases in a tertiary health facility in Nigeria: Description and lessons learned, 2018.2018 年尼日利亚一家三级医疗机构发生的一组医院感染拉沙热病例:描述和经验教训。
Int J Infect Dis. 2019 Jun;83:88-94. doi: 10.1016/j.ijid.2019.03.030. Epub 2019 Mar 28.
10
Knowledge of Lassa fever and use of infection prevention and control facilities among health care workers during Lassa fever outbreak in Ondo State, Nigeria.尼日利亚翁多州拉沙热疫情期间医护人员对拉沙热的认知及感染预防与控制设施的使用情况。
Pan Afr Med J. 2018 May 24;30:56. doi: 10.11604/pamj.2018.30.56.13125. eCollection 2018.