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四种饮食指数与心血管疾病患者死亡风险之间的关联。

The association between four dietary indices and mortality risk in cardiovascular disease patients.

作者信息

Pan Mengshan, Yin Tongle, Yang Ying, Zhu Feiyun, Xu Jiamin, Chen Rucheng, Zheng Weijun

机构信息

School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China.

出版信息

Nutr Metab (Lond). 2025 Jul 1;22(1):67. doi: 10.1186/s12986-025-00966-5.

Abstract

BACKGROUND

The Planetary Healthy Diet Index-United States, the Healthy Diet Index, the Mediterranean Diet, and the Dietary Inflammation Index were linked to mortality rates in cardiovascular patients. This study investigated the relationship between these dietary patterns and all-cause mortality risk in U.S. cardiovascular patients from 2005 to 2006 to 2017-2018.

METHODS

Data were collected from adults aged 19 years and older participating in the National Health and Nutrition Examination Survey from 2005 to 2006 to 2017-2018. Dietary patterns were assessed for each survey cycle using 24-hour dietary recalls, and scores for the four dietary indices were calculated. Survey-weighted multivariable Cox proportional hazards regression models evaluated associations between these indices and all-cause and cause-specific mortality among patients with cardiovascular disease, using hazard ratios across quartiles and per 1-SD increment.

RESULTS

This study included 3,088 patients with cardiovascular disease. In the partially adjusted model, the Planetary Healthy Diet Index-United States (HR = 0.81; 95% CI: 0.75-0.87; P < 0.001), Healthy Eating Index (HR = 0.85; 95% CI: 0.78-0.93; P < 0.001), and the Mediterranean Diet (HR = 0.82; 95% CI: 0.75-0.90; P < 0.001) were each associated with a reduced risk of all-cause mortality. In contrast, the Dietary Inflammatory Index was associated with an increased risk of all-cause mortality (HR = 1.25; 95% CI: 1.14-1.37; P < 0.001). In the fully adjusted model, the Planetary Healthy Diet Index-United States (HR = 0.89; 95% CI: 0.81-0.97; P = 0.005) remained significantly associated with a lower risk of all-cause mortality, whereas the Dietary Inflammation Index (HR = 1.20; 95% CI: 1.07-1.34; P = 0.002) continued to show a significant association with increased mortality risk.

CONCLUSIONS

Among cardiovascular disease patients, higher adherence to the Healthy Eating Index, Mediterranean Diet, and Planetary Healthy Diet Index-United States was linked to lower all-cause mortality, while higher Dietary Inflammation Index scores were linked to increased mortality. The Mediterranean Diet and Planetary Healthy Diet Index-United States were inversely associated with mortality in congestive heart failure patients, whereas Dietary Inflammation Index was positively associated with mortality in this group and in those with angina pectoris.

摘要

背景

美国行星健康饮食指数、健康饮食指数、地中海饮食和饮食炎症指数与心血管疾病患者的死亡率相关。本研究调查了2005年至2006年至2017年至2018年美国心血管疾病患者的这些饮食模式与全因死亡风险之间的关系。

方法

收集2005年至2006年至2017年至2018年参加美国国家健康和营养检查调查的19岁及以上成年人的数据。在每个调查周期中,使用24小时饮食回顾法评估饮食模式,并计算四个饮食指数的得分。采用调查加权多变量Cox比例风险回归模型,通过四分位数和每增加1个标准差的风险比,评估这些指数与心血管疾病患者全因和特定病因死亡率之间的关联。

结果

本研究纳入了3088例心血管疾病患者。在部分调整模型中,美国行星健康饮食指数(HR = 0.81;95%CI:0.75 - 0.87;P < 0.001)、健康饮食指数(HR = 0.85;95%CI:0.78 - 0.93;P < 0.001)和地中海饮食(HR = 0.82;95%CI:0.75 - 0.90;P < 0.001)均与全因死亡风险降低相关。相比之下,饮食炎症指数与全因死亡风险增加相关(HR = 1.25;95%CI:1.14 - 1.37;P < 0.001)。在完全调整模型中,美国行星健康饮食指数(HR = 0.89;95%CI:0.81 - 0.97;P = 0.005)仍与较低的全因死亡风险显著相关,而饮食炎症指数(HR = 1.20;95%CI:1.07 - 1.34;P = 0.002)继续显示与死亡风险增加显著相关。

结论

在心血管疾病患者中,更高程度地遵循健康饮食指数、地中海饮食和美国行星健康饮食指数与较低的全因死亡率相关,而较高的饮食炎症指数得分与死亡率增加相关。地中海饮食和美国行星健康饮食指数与充血性心力衰竭患者的死亡率呈负相关,而饮食炎症指数与该组患者以及心绞痛患者的死亡率呈正相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91a6/12211250/19dbde47a1b6/12986_2025_966_Fig1_HTML.jpg

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