Jansson L
Scand J Haematol. 1985 Sep;35(3):363-6. doi: 10.1111/j.1600-0609.1985.tb01721.x.
A graph of the relationship between mean platelet volume (MPV) and platelet count (TPK) was constructed out of 158 haematologically normal individuals, 19 patients with thrombocytopenia and 63 patients with thrombocytosis. Patients with thrombocytopenia and thrombocytosis whose bone marrows were found to show adequate or increased, morphologically normal, thrombopoiesis were included in the graph. The graph was found to exhibit the previously known inverse relationship between TPK and MPV extended into thrombocytopenic values and is thought to represent an intact marrow function capable of meeting the increased demands of thrombopoiesis. On the other hand, 15 patients whose bone marrows were showing evidence of hypoplastic thrombopoiesis fell outside the region representing intact marrow function. The position of an individual's values of MPV vs TPK in a coordinate system with these variables on the axes correlates well with the morphologic evaluation of thrombopoietic function and seems to be clinically useful.
基于158名血液学正常个体、19名血小板减少症患者和63名血小板增多症患者的数据，构建了平均血小板体积（MPV）与血小板计数（TPK）之间关系的图表。骨髓检查显示有足够的或增加的、形态正常的血小板生成的血小板减少症和血小板增多症患者被纳入该图表。结果发现该图表呈现出TPK与MPV之间先前已知的反比关系，这种关系延伸至血小板减少值范围，并且被认为代表了能够满足血小板生成增加需求的完整骨髓功能。另一方面，15名骨髓显示有血小板生成低下证据的患者落在代表完整骨髓功能的区域之外。在一个以这些变量为坐标轴的坐标系中，个体的MPV值与TPK值的位置与血小板生成功能的形态学评估密切相关，并且似乎具有临床实用性。
