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评估堪萨斯城心肌病问卷(KCCQ)评分对东南亚心力衰竭患者6个月再入院情况的预后价值。

Evaluating the Prognostic Value of Kansas City Cardiomyopathy Questionnaire (KCCQ) Scores for 6-Month Readmissions in Southeast Asian Populations With Heart Failure.

作者信息

Ong Jeanne Sy, Kham Ming Fatt, Goh Jonah, Phng Francis, Chan Po Fun, Loh Poay Huan, Wu Christine

机构信息

Department of Medicine, Ng Teng Fong General Hospital, Singapore, Singapore.

Health Services Research & Analytics, Ng Teng Fong General Hospital, Singapore, Singapore.

出版信息

Clin Cardiol. 2025 Jul;48(7):e70136. doi: 10.1002/clc.70136.

Abstract

BACKGROUND

Heart failure (HF) is a prevalent cause of hospital readmissions. Our study aims to determine the correlation between the Kansas City Cardiomyopathy Questionnaire (KCCQ) scores and 6-month readmission in our Southeast Asian population.

METHODS

We evaluated KCCQ-12 in a cohort of 180 patients at first post-discharge visit after a recent hospitalization for HF with reduced ejection fraction (HFrEF). Logistic regression was used to determine the predictive significance of the KCCQ scores for 6-month HF readmission. The selection of predictive parameters was performed using Stepwise Akaike Information Criterion (StepAIC).

RESULTS

Out of 180 patients, 52 (29%) were readmitted for HF within 6 months. The mean KCCQ score was higher in the non-readmitted group (78.5) compared to the readmitted group (69.7, p = 0.0129). Multivariate analysis indicated a significant association between higher KCCQ scores (better health status) and lower HF readmission rates (adjusted OR = 0.929, p = 0.0255). The initial predictive model, using patient demographic data, had an AUC score of 0.64. Integrating KCCQ scores with demographics, length of stay (LOS), medical history and discharge medication variables raised the AUC score to 0.82.

CONCLUSION

KCCQ scores recorded at first post-discharge encounter were found to have a significant relationship with 6-month readmissions in our cohort, suggesting that KCCQ scores can serve as an effective clinical indicator of 6 month readmissions.

摘要

背景

心力衰竭(HF)是导致患者再次入院的常见原因。我们的研究旨在确定堪萨斯城心肌病问卷(KCCQ)得分与东南亚人群6个月内再次入院之间的相关性。

方法

我们对180例近期因射血分数降低的心力衰竭(HFrEF)住院后首次出院随访的患者进行了KCCQ - 12评估。采用逻辑回归确定KCCQ得分对6个月内心力衰竭再次入院的预测意义。使用逐步赤池信息准则(StepAIC)进行预测参数的选择。

结果

180例患者中,52例(29%)在6个月内因心力衰竭再次入院。未再次入院组的KCCQ平均得分(78.5)高于再次入院组(69.7,p = 0.0129)。多变量分析表明,较高的KCCQ得分(更好的健康状况)与较低的心力衰竭再次入院率之间存在显著关联(调整后的OR = 0.929,p = 0.0255)。使用患者人口统计学数据的初始预测模型的AUC得分为0.64。将KCCQ得分与人口统计学、住院时间(LOS)、病史和出院用药变量相结合,使AUC得分提高到0.82。

结论

我们发现首次出院时记录的KCCQ得分与队列中6个月内的再次入院有显著关系,这表明KCCQ得分可作为6个月再次入院的有效临床指标。

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