Rodríguez-Sánchez Sara, Fernández-Pacheco Pilar, de Los Reyes-Ramos Cristina, Burgos-Ramos Emma, Seseña Susana, Palop M Llanos
Departamento de Química Analítica y Tecnología de Alimentos, Facultad de Ciencias Ambientales y Bioquímica Universidad de Castilla-La Mancha (UCLM) Toledo España.
Departamento de Química Inorgánica, Orgánica y Bioquímica, Facultad de Ciencias Ambientales y Bioquímica Universidad de Castilla-La Mancha (UCLM) Toledo España.
Food Sci Nutr. 2025 Jun 30;13(7):e70539. doi: 10.1002/fsn3.70539. eCollection 2025 Jul.
Functional foods consumption, included the synbiotics, has garnered attention of the consumers because of their health's benefits, being lactic acid bacteria (LAB) the microorganisms most used for their manufacturing. Twelve potential probiotic LAB strains were evaluated for cholesterol removal, phenolic content, antioxidant properties, α-glucosidase inhibitory activity (anti-diabetic effect), and in vitro angiotensin-I-converting enzyme- (ACE) inhibitory activity (anti-hypertensive effect), together with the assimilatory capacity of different prebiotics such as inulin, lactulose, β-glucans, and fructooligosaccharides, to be used in the production of a synbiotic yogur. Their anti-inflammatory potential in Caco-2 cells was also assayed. (.) UCLM-104 and (.) UCLM-41, exhibited interesting health promoting properties and an effective modulation of inflammation. Sensory analysis of the synbiotic yogurts manufactured with each of the strains displayed no significant differences between them, but there were statistically significant differences with the control yogurt, garnering greater acceptance from taste-testers. Therefore, both strains emerge as promising probiotic candidates to be used to produce synbiotic yogurts with potential health-promoting attributes and sensory appeal. This study represents a pioneering endeavor, being the first to comprehensively evaluate the health-enhancing properties of potential probiotic strains and subsequently apply them in the production of synbiotic yogurts.
食用功能性食品,包括合生元,因其对健康有益而受到消费者关注,乳酸菌(LAB)是用于生产功能性食品的最常用微生物。对12株潜在的益生菌LAB菌株进行了评估,测定其胆固醇去除能力、酚类含量、抗氧化性能、α-葡萄糖苷酶抑制活性(抗糖尿病作用)和体外血管紧张素I转换酶(ACE)抑制活性(抗高血压作用),以及它们对菊粉、乳果糖、β-葡聚糖和低聚果糖等不同益生元的同化能力,以用于生产合生元酸奶。还测定了它们在Caco-2细胞中的抗炎潜力。UCLM-104和UCLM-41表现出有趣的健康促进特性和对炎症的有效调节作用。用每种菌株生产的合生元酸奶的感官分析显示,它们之间没有显著差异,但与对照酸奶有统计学显著差异,更受味觉测试者的欢迎。因此,这两种菌株都是很有前景的益生菌候选菌株,可用于生产具有潜在健康促进特性和感官吸引力的合生元酸奶。本研究是一项开创性的工作,首次全面评估了潜在益生菌菌株的健康增强特性,并随后将其应用于合生元酸奶的生产。