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55只犬在接受手术减压(有无预防性开窗)后颈椎间盘突出的复发情况。

Recurrence of cervical intervertebral disc extrusion in 55 dogs after surgical decompression with or without prophylactic fenestration.

作者信息

Berthomé Clémence, Castel Aude, Malenfant Renée-Claire, Juette Tristan, Gagnon Dominique

机构信息

Faculté de médecine vétérinaire (FMV), Université de Montréal, Saint-Hyacinthe, Québec, Canada.

Surgery Department, Centre Vétérinaire Daubigny, Québec City, Québec, Canada.

出版信息

Vet Surg. 2025 Aug;54(6):1062-1072. doi: 10.1111/vsu.14303. Epub 2025 Jul 2.

DOI:10.1111/vsu.14303
PMID:40600629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12344229/
Abstract

OBJECTIVE

To determine whether prophylactic fenestration (PF) of adjacent intervertebral discs decreases the recurrence rate (RR) of cervical intervertebral disc extrusion (C-IVDE) in small dogs undergoing ventral slot (VS) decompression, and whether PF increases perioperative complication risk.

STUDY DESIGN

Retrospective, multi-institutional cohort study.

SAMPLE POPULATION

A total of 55 dogs.

METHODS

Medical records of a mixed population of small dogs (<20 kg) treated with VS for C-IVDE with a minimum one-year follow-up were reviewed. During surgery, dogs underwent either single-site PF, multiple-site PF, or no PF. Perioperative complication rate and RR were compared between PF and non-PF groups using generalized linear models. Surgical time and neurologic grade (presurgery, post-surgery, at first recheck) were compared with Mann-Whitney test and chi-squared tests.

RESULTS

A total of 55 dogs were included (PF: n = 18; non-PF: n = 37). Neurologic grades were similar at all timepoints. Median time to first recheck was 14 days (range: 5-56). Median follow-up time was 1380 days (range: 365-2777). Recurrence occurred in 25% of dogs (14/55), all in the non-PF group. Prophylactic fenestration was associated with a lower RR (p < .001). Surgery duration was longer in the PF group (158.0 ± 13.5 min) versus non-PF (118.0 ± 6.8 min, p = .017), but complication rates were similar (18.2%, p = .838) between groups.

CONCLUSION

Recurrence of C-IVDE is more likely to occur at non-PF group than PF-group in a heterogenous population of small breed dogs. Prophylactic fenestration was not linked to increased complication risk.

CLINICAL SIGNIFICANCE

Prophylactic fenestration might be safely considered to prevent C-IVDE recurrence.

摘要

目的

确定在接受腹侧开槽(VS)减压的小型犬中,对相邻椎间盘进行预防性开窗(PF)是否能降低颈椎间盘突出症(C-IVDE)的复发率(RR),以及PF是否会增加围手术期并发症风险。

研究设计

回顾性、多机构队列研究。

样本量

共55只犬。

方法

回顾了接受VS治疗C-IVDE的小型犬(体重<20 kg)的混合群体的病历,随访时间至少为一年。手术过程中,犬只接受单部位PF、多部位PF或不进行PF。使用广义线性模型比较PF组和非PF组的围手术期并发症发生率和RR。采用Mann-Whitney检验和卡方检验比较手术时间和神经学分级(术前、术后、首次复查时)。

结果

共纳入55只犬(PF组:n = 18;非PF组:n = 37)。所有时间点的神经学分级相似。首次复查的中位时间为14天(范围:5 - 56天)。中位随访时间为1380天(范围:365 - 2777天)。25%的犬(14/55)出现复发,均在非PF组。预防性开窗与较低的RR相关(p < .001)。PF组的手术时间(158.0 ± 13.5分钟)比非PF组(118.0 ± 6.8分钟,p = .017)长,但两组的并发症发生率相似(18.2%,p = .838)。

结论

在小型犬的异质群体中,C-IVDE在非PF组比PF组更易复发。预防性开窗与并发症风险增加无关。

临床意义

可安全考虑采用预防性开窗来预防C-IVDE复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfcd/12344229/baa5779864a7/VSU-54-1062-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfcd/12344229/baa5779864a7/VSU-54-1062-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfcd/12344229/baa5779864a7/VSU-54-1062-g001.jpg

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本文引用的文献

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Front Vet Sci. 2023 May 12;10:1148802. doi: 10.3389/fvets.2023.1148802. eCollection 2023.
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MRI and clinical findings in 133 dogs with recurrent deficits following intervertebral disc extrusion surgery.MRI 与临床检查在经历椎间盘突出手术后复发神经症状的 133 例犬只中的表现
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Recurrence rate of intervertebral disc disease in surgically treated French Bulldogs: a retrospective study (2009-2019).
手术治疗法国斗牛犬椎间盘疾病的复发率:一项回顾性研究(2009-2019 年)。
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Prophylactic Effect of Fenestration on the Recurrence of Thoracolumbar Intervertebral Disc Disease in Dogs.开窗术对犬胸腰椎间盘疾病复发的预防作用
Animals (Basel). 2022 Sep 28;12(19):2601. doi: 10.3390/ani12192601.
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ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion.ACVIM 共识声明:犬胸腰椎间盘突急性症的诊断与管理
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Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs.犬颈椎间盘突出症复发的症状。
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Late onset recurrence of clinical signs after surgery for intervertebral disc extrusion in French bulldogs.法国斗牛犬椎间盘挤出手术后临床症状迟发复发。
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