Xu Junzhu, Xia Xiujiao, Liu Zehu
Department of Dermatology, Hangzhou Third People's Hospital, No. 38 West Lake Avenue Road, Hangzhou, 310009, Zhejiang, China.
Parasitol Res. 2025 Jul 2;124(7):75. doi: 10.1007/s00436-025-08524-x.
This study presents the case of a 54-year-old woman, otherwise healthy, who presented with a 4-month history of red plaques with central ulceration, which had initially developed from painless papules. The lesions appeared on her right arm and trunk, two months after her travel to Morocco. Physical examination revealed a 7 cm × 5 cm red plaque with central ulceration and crusting on her right arm, along with papules and plaques on her trunk. Based on microbiological, histopathological, and PCR results, the patient was diagnosed with Old World cutaneous leishmaniasis. After receiving two sessions of intralesional pentavalent antimonial treatment, the patient was left with only a minor scar and experienced negligible side effects, except for moderate aching during therapy.
本研究报告了一名54岁的健康女性病例,她出现了4个月的红色斑块伴中央溃疡病史,最初由无痛性丘疹发展而来。这些病变出现在她的右臂和躯干上,是在她前往摩洛哥旅行两个月后出现的。体格检查发现她右臂有一个7厘米×5厘米的红色斑块,中央溃疡并有结痂,同时躯干上有丘疹和斑块。根据微生物学、组织病理学和聚合酶链反应结果,该患者被诊断为旧世界皮肤利什曼病。在接受了两疗程的病灶内五价锑治疗后,患者仅留下轻微疤痕,除治疗期间有中度疼痛外,副作用可忽略不计。