Paudel Kiran, Gautam Kamal, Pandey Anjila, Bhandari Prashamsa, Wickersham Jefferey A, Dhakal Manisha, Sujan Md Safaet Hossain, Acharya Bibhav, Sapkota Sabitri, Shrestha Archana, Shrestha Roman
Nepal Health Frontiers, Tokha-5, Kathmandu, Nepal.
Department of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Sci Rep. 2025 Jul 2;15(1):23087. doi: 10.1038/s41598-025-92449-z.
The increase in the chemsex phenomenon among gay, bisexual, and other men who have sex with men (GBMSM) is alarming, as it is associated with risky sexual behaviors, including condomless sex and multiple sex partners. Despite increasing concerns, there is nonexistent research on chemsex among GBMSM in Nepal. Therefore, our study aimed to identify the prevalence and factors associated with engagement in chemsex among GBMSM in Nepal. A cross-sectional online survey of 842 Nepali GBMSM was conducted between March and May 2024. Multivariable logistic regression was used to identify factors associated with chemsex engagement within the past 12 months. Among 842 participants (mean age 27.6 ± 7.1 years), 24.7% reported ever engaging in chemsex, and 19.1% did so in the past 12 months. GBMSM who had completed high school were less likely to have engaged in chemsex in the past 12 months (aOR: 0.5; 95% CI: 0.3-0.8). However, GBMSM who reported having multiple sex partners (aOR: 9.6; 95% CI: 1.3-71.4), being involved in party/group sex in the past 12 months (aOR: 2.5; 95% CI: 1.5-3.9), and with depressive symptoms (aOR: 2.0; 95% CI: 1.3-3.0) were more likely to have engaged in chemsex in the past 12 months. An integrated approach is urgently needed, encompassing awareness raising, safe drug use support, sexual health services, and mental health care.
男同性恋者、双性恋者及其他与男性发生性行为的男性（GBMSM）中“化学性爱”现象的增加令人担忧，因为它与危险性行为有关，包括无保护性行为和多个性伴侣。尽管人们越来越关注，但尼泊尔针对GBMSM群体中“化学性爱”的研究却不存在。因此，我们的研究旨在确定尼泊尔GBMSM群体中“化学性爱”的流行率及其相关因素。2024年3月至5月，我们对842名尼泊尔GBMSM进行了横断面在线调查。采用多变量逻辑回归分析来确定过去12个月内与“化学性爱”行为相关的因素。在842名参与者（平均年龄27.6±7.1岁）中，24.7%的人报告曾有过“化学性爱”行为，19.1%的人在过去12个月内有过此类行为。在过去12个月内，完成高中学业的GBMSM参与“化学性爱”的可能性较小（调整后比值比：0.5；95%置信区间：0.3 - 0.8）。然而，报告有多个性伴侣（调整后比值比：9.6；95%置信区间：1.3 - 71.4）、在过去12个月内参与过派对/群体性行为（调整后比值比：2.5；95%置信区间：1.5 - 3.9）以及有抑郁症状（调整后比值比：2.0；95%置信区间：1.3 - 3.0）的GBMSM在过去12个月内更有可能参与“化学性爱”。迫切需要一种综合方法，包括提高认识、提供安全用药支持、性健康服务和心理健康护理。
