Levene M B, Harris J R, Hellman S
Cancer. 1977 Jun;39(6 Suppl):2840-5. doi: 10.1002/1097-0142(197706)39:6<2840::aid-cncr2820390672>3.0.co;2-y.
One hundred and fifty patients with carcinoma of the breast were treated by radiation therapy without mastectomy. Seventy-seven patients had excisional biopsy of the breast mass while the remainder had incisional biopsy or needle biopsy. There has been 100% local control in patients with Stage I or Stage II disease. The local control rate in Stage III is 67.5%. Those patients who had excisional biopsy had a significantly lower incidence of local recurrence than did those in whom the tumor was left in situ. The cumulative survival probability at five years is 100% for Stage I, 65% for Stage II and 26% for Stage III. Recommendations are made concerning axillary node sampling and adjuvant chemotherapy for patients treated by this technique.
150例乳腺癌患者接受了保乳放疗。77例患者进行了乳房肿块切除活检，其余患者进行了切取活检或针吸活检。I期或II期疾病患者的局部控制率为100%。III期的局部控制率为67.5%。进行切除活检的患者局部复发率明显低于肿瘤未切除的患者。I期患者五年累积生存概率为100%，II期为65%，III期为26%。针对采用该技术治疗的患者，就腋窝淋巴结取样和辅助化疗提出了建议。
