Suppr超能文献

新一代双波长激光与传统激光类型治疗兔颞下颌关节骨关节炎的疗效比较。

Comparison of the effectiveness of the new generation dual wavelength laser with the conventional laser type in treating rabbit model temporomandibular joint osteoarthritis.

作者信息

Karadayı Gizemnur, Akbulut Nihat, Deresoy Faik Alev, Altan Ahmet

机构信息

Oral and Maxillofacial Surgeon, T.R. Ministry of Health, Oral and Dental Health Hospital, Çorum, Turkey.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ondokuz Mayıs University, Samsun, Turkey.

出版信息

BMC Oral Health. 2025 Jul 2;25(1):980. doi: 10.1186/s12903-025-06331-5.

Abstract

BACKGROUND

This study compared the effects of low-level laser applications with different wavelengths on rabbits' temporomandibular joint regeneration capacity with experimentally induced osteoarthritis.

METHODS

This study used 23 male New Zealand white rabbits. The animals were randomly divided into three groups. Osteoarthritis was induced in all groups by injecting sodium monoiodoacetate into the rabbits' joints. The joints of the experimental animals in Group 1 (GRR laser-dual wavelength, n = 8) and Group 2 (Epic10 laser-conventional laser, n = 8) were treated with laser for 14 sessions. In the control group (n = 7), no treatment was performed after osteoarthritis was induced. After the end of laser therapy, the rabbits were sacrificed simultaneously, and the temporomandibular joints were removed. Defect filling percentage, osteochondral junction reconstruction, matrix staining, and cellular morphology were examined histopathologically.

RESULTS

There was a connection between the groups with defect filling, and a statistically significant difference was found (p = 0.005). When we examined whether there was a connection between the osteochondral junction and the groups, it was determined that there was no statistically significant connection (p = 1.000). It was determined that there was a significant connection between the groups with matrix staining (p = 0.001). There was a connection between cellular morphology and the groups. It was determined that there was a statistically significant connection (p = 0.018). The defect filling, matrix staining, and cellular morphology values in both laser groups were better than in the control group.

CONCLUSIONS

Low-level laser therapy can increase remodeling and improve tissue repair in temporomandibular joint osteoarthritis treatment. There was no significant difference between lasers at different wavelengths in treating temporomandibular joint osteoarthritis.

摘要

背景

本研究比较了不同波长的低强度激光照射对实验性诱导骨关节炎的家兔颞下颌关节再生能力的影响。

方法

本研究使用了23只雄性新西兰白兔。将动物随机分为三组。所有组均通过向兔关节内注射单碘乙酸钠诱导骨关节炎。第1组(GRR激光 - 双波长,n = 8)和第2组(Epic10激光 - 传统激光,n = 8)的实验动物关节接受14次激光治疗。在对照组(n = 7)中,诱导骨关节炎后不进行治疗。激光治疗结束后,同时处死兔子,取出颞下颌关节。通过组织病理学检查缺损填充百分比、骨软骨交界处重建、基质染色和细胞形态。

结果

在缺损填充方面,组间存在关联,且发现有统计学显著差异(p = 0.005)。当我们检查骨软骨交界处与组间是否存在关联时,确定不存在统计学显著关联(p = 1.000)。确定在基质染色方面组间存在显著关联(p = 0.001)。细胞形态与组间存在关联。确定存在统计学显著关联(p = 0.018)。两个激光组的缺损填充、基质染色和细胞形态值均优于对照组。

结论

低强度激光治疗可增加颞下颌关节骨关节炎治疗中的重塑并改善组织修复。不同波长的激光在治疗颞下颌关节骨关节炎方面无显著差异。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验