Shimodaira Yosuke, Fukuda Sho, Yoshida Tatsuki, Watanabe Kenta, Matsuhashi Tamotsu, Onochi Kengo, Iijima Katsunori
Department of Gastroenterology and Neurology, Akita University Graduate School of Medicine, Akita, Japan.
Division of Gastroenterology, Omagari Kosei Medical Center, Daisen, Japan.
Inflamm Intest Dis. 2025 May 23;10(1):161-168. doi: 10.1159/000546032. eCollection 2025 Jan-Dec.
Patients with ulcerative colitis are prone to mental disorders and may be under psychological burden due to the development of ulcerative colitis-associated cancer. Therefore, evidence regarding awareness and concerns about cancer development is needed. We aimed to investigate the state of awareness regarding cancer in patients with ulcerative colitis, and their concerns about cancer, awareness of risk factors, and information-gathering methods.
Questionnaires were administered to patients with ulcerative colitis who regularly visited our hospital. The Cancer Worry Scale was used to quantitatively evaluate the anxiety of developing cancer and the psychological burden in daily life. The Inflammatory Bowel Disease Questionnaire and the Short Form-8 were used to evaluate quality of life. Factors associated with cancer risk were also investigated.
A total of 112 patients were included; 78 patients have perceived a risk of developing colorectal cancer. Cancer Worry Scale for colorectal cancer was significantly higher than that for gastric cancer. Of the patients who answered that they perceived developing colorectal cancer with ulcerative colitis, 70% found more details about developing cancer by asking doctors; and 85.7% by using the internet and social networking services. The intestinal disease-specific self-administered questionnaire, Inflammatory Bowel Disease Questionnaire, score was associated with positive Cancer Worry Scale. In the Short Form-8, a lower Mental Component Summary was also associated with a positive Cancer Worry Scale.
Patients with ulcerative colitis can be affected by cancer worry. More scientific evidence, reliable information that patients can access, and accurate information conveyed by medical staff are required.
溃疡性结肠炎患者容易出现精神障碍，且可能因溃疡性结肠炎相关癌症的发生而承受心理负担。因此，需要有关癌症发生的认知及担忧方面的证据。我们旨在调查溃疡性结肠炎患者对癌症的认知状况、他们对癌症的担忧、对危险因素的认识以及信息收集方法。
对定期来我院就诊的溃疡性结肠炎患者进行问卷调查。使用癌症担忧量表定量评估患癌焦虑及日常生活中的心理负担。使用炎症性肠病问卷和简明健康调查问卷-8评估生活质量。还调查了与癌症风险相关的因素。
共纳入112例患者；其中78例患者意识到有患结直肠癌的风险。结直肠癌的癌症担忧量表得分显著高于胃癌。在回答自己意识到溃疡性结肠炎会发展为结直肠癌的患者中，70% 通过向医生咨询了解到更多癌症相关细节；85.7% 通过互联网和社交网络服务了解到相关信息。肠道疾病专用自填问卷即炎症性肠病问卷的得分与癌症担忧量表呈正相关。在简明健康调查问卷-8中，较低的心理成分总结得分也与癌症担忧量表呈正相关。
溃疡性结肠炎患者可能会受到癌症担忧的影响。需要更多科学证据、患者可获取的可靠信息以及医务人员传达的准确信息。
