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一名无危险因素的绝经后女性体内的巨大腹膜包涵囊肿。

A large peritoneal inclusion cyst in a postmenopausal female without risk factors.

作者信息

Rahmatullah Zahra F, Chu Linda C, Hruban Ralph H, Fishman Elliot K

机构信息

Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA.

Department of Pathology, Johns Hopkins University School of Medicine, 1800 Orleans Street, Baltimore, MD 21287, USA.

出版信息

Radiol Case Rep. 2025 Jun 19;20(9):4438-4443. doi: 10.1016/j.radcr.2025.05.081. eCollection 2025 Sep.

DOI:10.1016/j.radcr.2025.05.081
PMID:40606582
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12221492/
Abstract

Peritoneal inclusion cysts (PICs) are rare, benign cystic lesions most often seen in females of reproductive age with a history of peritoneal injury. This case presents a 55-year-old postmenopausal female with no known risk factors who developed a large PIC, causing abdominal pain, fullness, and distention. Imaging, including CT and MRI, revealed a lobulated, fluid-filled mass in the left peritoneal cavity, initially suspected to be a lymphangioma. MRI confirmed the presence of a multilocular cyst with enhancing septa. Surgical exploration identified the cyst as a PIC involving the jejunal mesentery, with final pathology confirming the benign nature of the lesion. While PICs are typically associated with premenopausal females and peritoneal trauma, this case highlights their potential occurrence in postmenopausal age groups without prior insults. The ability to recognize characteristic imaging features-such as cystic lesions with enhancing septa on CT and MRI-can help differentiate PICs from other cystic abdominal masses, including lymphangiomas and neoplastic cystic masses.

摘要

腹膜包涵囊肿(PICs)是一种罕见的良性囊性病变,多见于有腹膜损伤史的育龄女性。本病例为一名55岁的绝经后女性,无已知危险因素,却出现了一个巨大的腹膜包涵囊肿,导致腹痛、腹胀和腹部膨隆。包括CT和MRI在内的影像学检查显示,左腹膜腔内有一个分叶状、充满液体的肿块,最初怀疑是淋巴管瘤。MRI证实存在一个有强化分隔的多房囊肿。手术探查发现该囊肿为累及空肠系膜的腹膜包涵囊肿,最终病理证实了病变的良性性质。虽然腹膜包涵囊肿通常与绝经前女性和腹膜创伤有关,但本病例凸显了它们在无既往损伤的绝经后年龄组中发生的可能性。识别特征性影像学表现的能力,如CT和MRI上有强化分隔的囊性病变,有助于将腹膜包涵囊肿与其他腹部囊性肿块,包括淋巴管瘤和肿瘤性囊性肿块区分开来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/61f1c984c38e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/7a55c2a9cfa3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/d651afd0100e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/0cb4d2a7b7bb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/61f1c984c38e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/7a55c2a9cfa3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/d651afd0100e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/0cb4d2a7b7bb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adda/12221492/61f1c984c38e/gr4.jpg

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本文引用的文献

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A case report of a rare etiology of an abdominal cystic lesion in adults: Peritoneal inclusion cysts.一例成人腹部囊性病变罕见病因的病例报告:腹膜包涵囊肿。
Int J Surg Case Rep. 2025 Jan;126:110792. doi: 10.1016/j.ijscr.2024.110792. Epub 2024 Dec 26.
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Large and Extensive Multilocular Peritoneal Inclusion Cysts Lack Genomic Alterations and Follow an Indolent Clinical Course Despite Rare Recurrences.大而广泛的多房性腹膜包涵囊肿缺乏基因组改变,尽管罕见复发,但临床病程呈惰性。
Am J Surg Pathol. 2024 Sep 1;48(9):1177-1184. doi: 10.1097/PAS.0000000000002249. Epub 2024 May 30.
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Approach to Cystic Lesions in the Abdomen and Pelvis, with Radiologic-Pathologic Correlation.
腹部和骨盆囊性病变的处理方法:放射-病理相关性。
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