Wang Chen, Hu Hong, Song Yun, Wang Yu-Gang, Shi Min
Department of Gastroenterology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China.
Department of Gastroenterology, Shanghai Tongren Hospital, Shanghai 200000, China.
World J Hepatol. 2025 Jun 27;17(6):107299. doi: 10.4254/wjh.v17.i6.107299.
A study published by Teerasarntipan in the provides valuable insights into prognostic scoring for acute liver failure and in-hospital mortality in patients with dengue-induced severe hepatitis. Their findings validate the model for end-stage liver disease score as the most reliable predictor while demonstrating the utility of the simpler Easy Albumin-Bilirubin score. Despite these findings, current prognostic models face limitations in real-world clinical applications. This letter discusses the strengths and weaknesses of current prognostic models, proposes future directions for improving prognostic accuracy and clinical implementations. This letter also broadens the horizons of prognostic models for liver dysfunction caused by other viral infections.
Teerasarntipan发表的一项研究为登革热所致严重肝炎患者的急性肝衰竭预后评分及院内死亡率提供了有价值的见解。他们的研究结果证实终末期肝病评分模型是最可靠的预测指标，同时也证明了更简单的简易白蛋白-胆红素评分的实用性。尽管有这些发现，但目前的预后模型在实际临床应用中仍存在局限性。这封信讨论了当前预后模型的优缺点，提出了提高预后准确性和临床应用的未来方向。这封信还拓宽了其他病毒感染所致肝功能障碍预后模型的视野。
