Wang Zhuoran, Huang Xianchao, Li Daowu, Zhou Wei, Wang Yingjie, Zeng Xiangtao, Zhang Zexin, Zheng Yushuang, Pan Weiyan, Zhu Meiling, Wei Qing, Yuan Hang, Li Xiaoxuan, Zhang Zhiming, Wei Long
Beijing Engineering Research Centre of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
School of Nuclear Science and Technology, University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Phys Med Biol. 2025 Jul 16;70(14). doi: 10.1088/1361-6560/adebd9.
The monolithic crystal detector has attracted attention due to its high detection efficiency and intrinsic depth of interaction resolution. However, the inherent edge effects degrade the performance at the boundaries of the detector, resulting in reduced positioning accuracy. To address this issue, this paper proposes a dual-ended readout positron emission tomography (PET) detector based on neighboring monolithic crystal light sharing. By combining the advantages of light sharing and dual-ended readout, the spatial resolution at the edges of the monolithic crystal detector is improved.Four LYSO crystals measuring40×40×20 mmwere utilized in this paper. A high-refractive-index optical adhesive was employed to bond the polished sides of the four crystals into a cohesive unit. In the two-dimensional plane positioning of the detector, the center of gravity method is employed using a threshold reduction and a combined response calculation of the neighboring crystal light sharing.The results indicate that the dual-ended readout detector based on light sharing achieves spatial resolution results in the light-sharing area that are comparable to those in the central area, yielding a spatial resolution of 0.76 mm on the= 0 plane of a 20 mm thick crystal detector, significantly mitigating the edge effects of the monolithic crystal detector. Furthermore, the single-ended readout detector utilizing the light sharing technique has achieved a spatial resolution of 0.99 mm.The dual-ended readout detector utilizing light sharing among neighboring crystals effectively addresses the edge effect issue encountered in monolithic crystal detectors, thereby achieving high spatial resolution in thick crystals. This innovative approach presents an advantageous detector scheme for the advancement of high-sensitivity, high-spatial-resolution small animal PET.
整块晶体探测器因其高探测效率和固有的相互作用深度分辨率而受到关注。然而,固有的边缘效应会降低探测器边界处的性能,导致定位精度降低。为了解决这个问题,本文提出了一种基于相邻整块晶体光共享的双端读出正电子发射断层扫描(PET)探测器。通过结合光共享和双端读出的优点,提高了整块晶体探测器边缘处的空间分辨率。本文使用了四块尺寸为40×40×20 mm的LYSO晶体。采用高折射率光学粘合剂将四块晶体的抛光面粘结成一个连贯的单元。在探测器的二维平面定位中,采用重心法,通过降低阈值和对相邻晶体光共享进行联合响应计算。结果表明,基于光共享的双端读出探测器在光共享区域的空间分辨率与中心区域相当,在20 mm厚的晶体探测器的= 0平面上空间分辨率为0.76 mm,显著减轻了整块晶体探测器的边缘效应。此外,利用光共享技术的单端读出探测器实现了0.99 mm的空间分辨率。利用相邻晶体间光共享的双端读出探测器有效地解决了整块晶体探测器中遇到的边缘效应问题,从而在厚晶体中实现了高空间分辨率。这种创新方法为高灵敏度、高空间分辨率的小动物PET的发展提供了一种有利的探测器方案。