Beijing Engineering Research Centre of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
School of Nuclear Science and Technology, University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Phys Med Biol. 2024 Apr 3;69(8). doi: 10.1088/1361-6560/ad3417.
Monolithic crystal detectors are increasingly being applied in positron emission tomography (PET) devices owing to their excellent depth-of-interaction (DOI) resolution capabilities and high detection efficiency. In this study, we constructed and evaluated a dual-ended readout monolithic crystal detector based on a multiplexing method.We employed two 12 × 12 silicon photomultiplier (SiPM) arrays for readout, and the signals from the 12 × 12 array were merged into 12 X and 12 Y channels using channel multiplexing. In 2D reconstruction, three methods based on the centre of gravity (COG) were compared, and the concept of thresholds was introduced. Furthermore, a light convolutional neural network (CNN) was employed for testing. To enhance depth localization resolution, we proposed a method by utilizing the mutual information from both ends of the SiPMs. The source width and collimation effect were simulated using GEANT4, and the intrinsic spatial resolution was separated from the measured values.At an operational voltage of 29 V for the SiPM, an energy resolution of approximately 12.5 % was achieved. By subtracting a 0.8 % threshold from the total energy in every channel, a 2D spatial resolution of approximately 0.90 mm full width at half maximum (FWHM) can be obtained. Furthermore, a higher level of resolution, approximately 0.80 mm FWHM, was achieved using a CNN, with some alleviation of edge effects. With the proposed DOI method, a significant 1.36 mm FWHM average DOI resolution can be achieved. Additionally, it was found that polishing and black coating on the crystal surface yielded smaller edge effects compared to a rough surface with a black coating.The introduction of a threshold in COG method and a dual-ended readout scheme can lead to excellent spatial resolution for monolithic crystal detectors, which can help to develop PET systems with both high sensitivity and high spatial resolution.
整体式晶体探测器由于其优异的深度分辨率能力和高检测效率,越来越多地应用于正电子发射断层扫描(PET)设备中。在这项研究中,我们构建并评估了一种基于复用方法的双端读出整体式晶体探测器。我们使用两个 12×12 的硅光电倍增管(SiPM)阵列进行读出,通过通道复用将 12×12 阵列的信号合并为 12X 和 12Y 通道。在 2D 重建中,比较了基于重心(COG)的三种方法,并引入了阈值的概念。此外,还使用了一个轻量级卷积神经网络(CNN)进行测试。为了提高深度定位分辨率,我们提出了一种利用 SiPM 两端互信息的方法。使用 GEANT4 模拟源宽度和准直效果,并从测量值中分离出固有空间分辨率。在 SiPM 的工作电压为 29V 时,能量分辨率约为 12.5%。通过从每个通道的总能量中减去 0.8%的阈值,可以获得大约 0.90mm 全宽半最大值(FWHM)的 2D 空间分辨率。此外,使用 CNN 可以获得更高的分辨率,大约为 0.80mm FWHM,同时减轻了边缘效应。使用所提出的 DOI 方法,可以实现 1.36mm FWHM 的平均 DOI 分辨率。此外,与具有黑色涂层的粗糙表面相比,在晶体表面进行抛光和黑色涂层处理可以产生较小的边缘效应。在 COG 方法中引入阈值和双端读出方案可以为整体式晶体探测器带来优异的空间分辨率,有助于开发具有高灵敏度和高空间分辨率的 PET 系统。