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现实环境中的支气管内超声引导下经支气管针吸活检术

Endobronchial ultrasound-guided transbronchial needle aspiration in real-life settings.

作者信息

Çoşğun İbrahim Güven, Balcı Aydın, Çilekar Şule

机构信息

Afyonkarahisar Health Sciences University, Department of Pulmonology, Afyonkarahisar, Turkey.

出版信息

Respir Med. 2025 Sep;246:108239. doi: 10.1016/j.rmed.2025.108239. Epub 2025 Jul 1.

Abstract

BACKGROUND

Endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) is an important method in staging lung cancer and diagnosing diseases causing mediastinal lymphadenopathy. Most studies confirming the performance of EBUS-TBNA have been prospective studies with strict protocols. This study aimed to evaluate the diagnostic accuracy in real life in a tertiary-level hospital.

METHODS

A retrospective evaluation was made of patients who underwent transbronchial needle aspiration (TBNA) with endobronchial ultrasound (EBUS) between January 2019 and December 2023. The results obtained from invasive surgery performed on patients with a negative result were compared with the EBUS-TBNA results.

RESULTS

Evaluation was made of 279 patients, comprising 177 males and 102 females with a mean age of 60.11 years (range, 20-87 years). A total of 569 lymph node stations were sampled. The diagnostic sensitivity of the EBUS-TBNA procedure was determined to be 86.4 %, the negative predictive value was 63 %, and the diagnostic success of EBUS-TBNA based on a definitive diagnosis was 89.2 %.

CONCLUSION

As the EBUS-TBNA procedure becomes more widespread, there is a need for evaluation in the field other than in specialized centers. The performance of EBUS-TBNA in our center was found to have a base accuracy of 89.2 % for all pathologies. As it is minimally invasive, is reliable, and has high diagnostic rates, it is worth promoting broader applications of EBUS-TBNA in thoracic lesions in non-specialized centers.

摘要

背景

支气管内超声引导针吸活检术(EBUS-TBNA)是肺癌分期及诊断引起纵隔淋巴结肿大疾病的重要方法。多数证实EBUS-TBNA性能的研究为遵循严格方案的前瞻性研究。本研究旨在评估一家三级医院在实际临床中的诊断准确性。

方法

对2019年1月至2023年12月期间接受支气管内超声引导针吸活检术(TBNA)的患者进行回顾性评估。将检查结果为阴性的患者接受的侵入性手术结果与EBUS-TBNA结果进行比较。

结果

共评估279例患者,其中男性177例,女性102例,平均年龄60.11岁(范围20-87岁)。共采集了569个淋巴结站。EBUS-TBNA检查的诊断敏感性为86.4%,阴性预测值为63%,基于明确诊断的EBUS-TBNA诊断成功率为89.2%。

结论

随着EBUS-TBNA检查的日益普及,除专业中心外,其他领域也需要进行评估。本中心EBUS-TBNA对所有病理类型的基础诊断准确率为89.2%。因其微创、可靠且诊断率高,值得在非专业中心更广泛地推广应用于胸部病变。

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