Romero Maria C O, Jakob Kevin, Schmidt Johannes, Nimmerfroh Thomas, Schwack Wolfgang, Morlock Gertrud E
Institute of Nutritional Science, Chair of Food Science, and Interdisciplinary Research Center (iFZ), Justus Liebig University Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.
Electronics Workshop, Department of Physics, Justus Liebig University Giessen, Heinrich-Buff-Ring 20, 35392 Giessen, Germany.
Anal Chim Acta. 2025 Sep 15;1367:344103. doi: 10.1016/j.aca.2025.344103. Epub 2025 Apr 20.
The miniaturized 2LabsToGo predecessor system consolidated most devices used in the planar chromatography laboratory and toxicological bioassay testing laboratory; however, important features for greater user convenience were still missing. It can be used for non-target chemical safety analysis of products on the global market or environmental samples to detect known and unknown hazardous compounds.
The system had to be redeveloped due to the many changes and improvements and was termed 2LabsToGo-Eco to make this difference recognizable. Twelve new key elements were implemented for the first time, such as solar panels for power supply-free operation, autosampler for hands-free application of samples, Mini-Shaker, Nebulizer, and Mini-Incubator as smart bioassay tools, superior tools for imaging, and electronic mainboard to eliminate cable and circuit board clutter. It was again designed open-source for do-it-yourself assembly. Miniaturization and dematerialization let to the reduction (compared to the status quo) of instrument investment costs by a factor of 35, starting capital by a factor of 18, weight by a factor of 12, infrastructure and bench space requirement by a factor of 9, and power supply by a factor of 4 or even 711 using solar energy. The new 2LabsToGo-Eco was proven and demonstrated for quantitative non-target safety analysis of cosmetics, personal care products, and foods.
For the first time, the sustainable 2LabsToGo-Eco is ready to go viral to allow for a non-target safety analysis with a prioritization strategy using the consolidated chromatography-bioassay lab. It boosts the transformation of laboratories towards sustainability, enables mobile on-site testing, allows customization of instruments, and democratizes access to chromatography and bioassay equipment.
小型化的2LabsToGo前身系统整合了平面色谱实验室和毒理学生物测定测试实验室中使用的大多数设备;然而,仍缺少一些能为用户带来更大便利的重要功能。它可用于对全球市场上的产品或环境样本进行非靶向化学安全分析,以检测已知和未知的有害化合物。
由于进行了诸多改变和改进,该系统必须重新开发,并命名为2LabsToGo-Eco,以便体现这些差异。首次采用了12个新的关键要素,如用于无电源运行的太阳能板、用于免手动进样的自动进样器、作为智能生物测定工具的迷你振荡器、雾化器和迷你培养箱、出色的成像工具以及用于消除电缆和电路板杂乱的电子主板。它再次被设计为开源,便于用户自行组装。小型化和去物质化使仪器投资成本(与现状相比)降低了35倍,启动资金降低了18倍,重量降低了12倍,基础设施和工作台空间需求降低了9倍,使用太阳能时电源需求降低了4倍甚至711倍。新型2LabsToGo-Eco已在化妆品、个人护理产品和食品的定量非靶向安全分析中得到验证和展示。
可持续的2LabsToGo-Eco首次准备好广泛传播,以便使用整合的色谱 - 生物测定实验室通过优先策略进行非靶向安全分析。它推动实验室向可持续发展转型,实现移动现场测试,允许仪器定制,并使色谱和生物测定设备的使用更加普及。