口服100毫克剂量强力霉素后24至30小时，人体输卵管黏膜和血浆中的强力霉素情况

Doxycycline in human oviduct mucosa and plasma 24-30 hours after an oral dose of 100 mg.

作者信息

Brihmer C, Brundin J

出版信息

Acta Obstet Gynecol Scand. 1985;64(6):529-30. doi: 10.3109/00016348509156734.

Abstract

Oviductal and peripheral plasma concentrations 24 hours after the last dose of Doxycycline (DC) were studied in 17 patients. The concentration of DC in healthy oviduct mucosa was 1.3 micrograms/g (range 0.6-1.7) and 1.1 micrograms/ml (range 0.6-1.7) in plasma. One patient with severe chronic salpingitis in acute exacerbation showed 3.6 micrograms/g in tissue and 2.4 micrograms/ml in plasma in proliferative phase.

摘要

对17例患者研究了最后一剂强力霉素（DC）24小时后的输卵管和外周血血浆浓度。健康输卵管黏膜中DC的浓度为1.3微克/克（范围0.6 - 1.7），血浆中为1.1微克/毫升（范围0.6 - 1.7）。1例处于急性加重期的重度慢性输卵管炎患者在增殖期组织中的浓度为3.6微克/克，血浆中为2.4微克/毫升。