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应用共同设计的药物治疗方案以实现老年人更安全的药物治疗:一项可行性研究。

Applying a co-designed medication plan for safer medication treatment in older persons: a feasibility study.

作者信息

Holmqvist Malin, Ros Axel, Thor Johan, Johansson Linda

机构信息

Department of Public Health and Healthcare, Region Jönköping County, Jönköping, Sweden.

Institute of Gerontology, School of Health and Welfare, Jönköping University, Jönköping, Sweden.

出版信息

Pilot Feasibility Stud. 2025 Jul 3;11(1):92. doi: 10.1186/s40814-025-01661-1.

Abstract

BACKGROUND

To promote patient safety, international guidelines highlight the importance of a joint plan for continued treatment in older persons. Accordingly, in a co-design initiative involving older persons and healthcare professionals, a medication plan was developed. This study aimed to assess the feasibility of applying the medication plan for older persons in primary care. The objectives were to examine the feasibility of the medication plan in clinical practice and to examine the feasibility of methods that could be used to study a broader implementation.

METHODS

A prospective study design, using both qualitative and quantitative methods, was employed. During appointments at primary care centres, physicians (n = 6), persons aged 75 or older (n = 21), and, when applicable, their next of kin (n = 2) collaboratively agreed on a medication plan, which was documented in the electronic health record. Over a 3-month follow-up period, data regarding the feasibility of the medication plan (usability and fidelity) and the feasibility of the research methods (recruitment and retention rates, data collection, and outcome measures) were collected.

RESULTS

Usability assessed by the System Usability Scale scored a median of 51.3 out of 100 for physicians. The participants' experiences of the medication plan's usability addressed functionalities, individualisation for relevance, resources, and a de-prioritised medication plan. Fidelity was assessed based on 8 out of 15 older persons reporting that they had received a medication plan, and 59% of all prescribed medications had documented goals and/or comments. The recruitment rate was 75% for physicians and 70% for older persons. There were no changes in polypharmacy and no contact with healthcare due to suspected adverse drug events. The participants' perceptions of the medication plan's ability to promote patient safety addressed awareness and information, challenges beyond the medication plan, and patient involvement.

CONCLUSIONS

The implementation of the co-designed medication plan encountered challenges related to usability and fidelity, requiring collaborative refinements of the prototype. Additional difficulties arose from using a low-fidelity prototype in clinical practice. Our results emphasise the strength of combining qualitative and quantitative methods to capture participants' perspectives on the medication plan's ability to promote patient safety. Before conducting a larger study, the evaluation methods require further refinement.

TRIAL REGISTRATION

ClinicalTrials.gov NCT06016140 (retrospectively registered).

摘要

背景

为促进患者安全,国际指南强调了针对老年人制定持续治疗联合计划的重要性。因此,在一项涉及老年人和医疗保健专业人员的共同设计倡议中,制定了一份用药计划。本研究旨在评估在初级保健中应用该老年人用药计划的可行性。目标是检验用药计划在临床实践中的可行性,并检验可用于研究更广泛实施情况的方法的可行性。

方法

采用前瞻性研究设计,同时使用定性和定量方法。在初级保健中心就诊期间,医生(n = 6)、75岁及以上的老年人(n = 21)以及(如适用)他们的近亲(n = 2)共同商定一份用药计划,并记录在电子健康记录中。在3个月的随访期内,收集了有关用药计划可行性(可用性和保真度)以及研究方法可行性(招募和保留率、数据收集和结果测量)的数据。

结果

通过系统可用性量表评估的医生可用性中位数为100分中的51.3分。参与者对用药计划可用性的体验涉及功能、相关性个性化、资源以及次要的用药计划。保真度根据15名老年人中有8人报告他们已收到用药计划以及所有处方药物中有59%记录了目标和/或注释来评估。医生的招募率为75%,老年人的招募率为70%。多重用药情况没有变化,也没有因疑似药物不良事件与医疗保健机构接触。参与者对用药计划促进患者安全能力的看法涉及意识和信息、用药计划之外的挑战以及患者参与。

结论

共同设计的用药计划的实施遇到了与可用性和保真度相关的挑战,需要对原型进行协作改进。在临床实践中使用低保真原型还产生了其他困难。我们的结果强调了结合定性和定量方法以获取参与者对用药计划促进患者安全能力看法的优势。在进行更大规模的研究之前,评估方法需要进一步完善。

试验注册

ClinicalTrials.gov NCT06016140(追溯注册)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f5/12224353/429eab4c67ae/40814_2025_1661_Fig1_HTML.jpg

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