Barros Gonçalo, Ribeiro Filipa
Universidade Católica Portuguesa, Faculty of Health Sciences and Nursing, CIIS, Portugal.
MethodsX. 2025 Jun 13;15:103439. doi: 10.1016/j.mex.2025.103439. eCollection 2025 Dec.
Obsessive-compulsive disorder (OCD) is characterized by deficits in inhibitory control and attentional processes. The emotional nature of stimuli can significantly influence these cognitive processes, yet traditional paradigms assessing inhibitory responses, such as the Stop-Signal Task, typically neglect emotional stimuli. This limitation reduces their capacity to capture the cognitive impairments associated with OCD fully. To address this gap, we introduce the Modified Emotional Stop-Signal Task (MESST), a novel paradigm designed to concurrently evaluate inhibitory control and attentional biases through eye-tracking technology. MESST integrates emotionally evocative stimuli into a standard stop-signal framework, allowing simultaneous measurement of Stop-Signal Reaction Time (SSRT) and attentional metrics such as latency to first fixation and total dwell time. Additionally, participants complete validated psychological scales-the State-Trait Anxiety Inventory (STAI), Barratt Impulsiveness Scale (BIS-11), and Obsessive-Compulsive Inventory-Revised (OCI-R)-providing detailed characterization of impulsivity and anxiety traits. Suitable for normative and clinical populations, MESST facilitates the investigation of interactions between emotional processing, cognitive control, and attentional biases, thereby advancing our understanding of the cognitive-emotional mechanisms underlying OCD and related disorders.•Integrates emotional stimuli into a standard inhibitory control paradigm.•Measures attentional processes concurrently via high-frequency eye-tracking.•Applicable to both clinical and non-clinical populations.
强迫症(OCD)的特征在于抑制控制和注意力过程存在缺陷。刺激的情感性质会显著影响这些认知过程,然而,评估抑制反应的传统范式,如停止信号任务,通常忽略情感刺激。这一局限性降低了它们全面捕捉与强迫症相关的认知障碍的能力。为了填补这一空白,我们引入了改良情感停止信号任务(MESST),这是一种新颖的范式,旨在通过眼动追踪技术同时评估抑制控制和注意力偏差。MESST将引发情感的刺激整合到标准的停止信号框架中,允许同时测量停止信号反应时间(SSRT)和注意力指标,如首次注视潜伏期和总停留时间。此外,参与者要完成经过验证的心理量表——状态-特质焦虑量表(STAI)、巴拉特冲动性量表(BIS-11)和强迫症量表修订版(OCI-R),以详细描述冲动性和焦虑特质。MESST适用于正常人群和临床人群,有助于研究情感加工、认知控制和注意力偏差之间的相互作用,从而增进我们对强迫症及相关障碍潜在的认知-情感机制的理解。
•将情感刺激整合到标准的抑制控制范式中。
•通过高频眼动追踪同时测量注意力过程。
•适用于临床和非临床人群。