Weil S C, Holt S, Hrisinko M A, Little L, DeBacker N
Am J Clin Pathol. 1985 Nov;84(5):679-81. doi: 10.1093/ajcp/84.5.679.
Dark pigmented inclusions were found in the monocytes and polymorphonuclear leukocytes of a patient with widely metastatic malignant melanoma. Special stains demonstrated the granules were composed of melanin. The authors are not aware of any previous case report of patients with metastatic malignant melanoma that had leukocytic melanin inclusions. Prospective search for this phenomenon in malignant melanoma patients may allow such a finding to be used as a diagnostic tool.
在一名广泛转移的恶性黑色素瘤患者的单核细胞和多形核白细胞中发现了深色色素沉着内含物。特殊染色显示这些颗粒由黑色素组成。作者不知道之前有任何关于转移性恶性黑色素瘤患者出现白细胞黑色素内含物的病例报告。对恶性黑色素瘤患者中这一现象进行前瞻性研究，可能会使这一发现用作一种诊断工具。
