Poochanasri Methavee, Kookanok Chutawat, Kaewput Wisit, Rangsin Ram, Sathavarodom Nattapol, Boonyavarakul Apussanee, Samakkarnthai Parinya
Division of Endocrinology, Department of Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, 10400, Thailand.
Department of Internal Medicine, Bhumibol Adulyadej Hospital, Bangkok, Thailand, 10220.
Diabetol Metab Syndr. 2025 Jul 4;17(1):254. doi: 10.1186/s13098-025-01781-x.
Obesity is an emerging public health issue and a significant risk factor for type 2 diabetes mellitus (T2DM). The growing prevalence of obesity in T2DM patients worsens disease outcomes, elevates medical expenses, and increases the risk of cardiovascular complications. Recognizing the trends and related factors of obesity in T2DM patients is essential for guiding specific interventions and public health strategies. This study aims to analyze the trends in obesity prevalence among T2DM patients in Thailand from 2014 to 2018 and to identify significant demographic, clinical, and lifestyle factors linked to obesity.
This sequential cross-sectional study utilized secondary data from the Thailand DM/HT database in 2014 and 2018. It did not include individuals under 18 or those with incomplete data. Descriptive statistics were used to analyze demographic characteristics and obesity prevalence, while multivariable logistic regression was employed to identify factors independently associated with obesity. Additionally, linear regression analysis assessed the relationships between BMI and continuous variables, including age, systolic blood pressure (SBP), and HbA1c levels.
A total of 32,196 patients in 2014 and 38,119 in 2018 were included. The prevalence of obesity among T2DM patients rose from 49.9% in 2014 to 51.1% in 2018, with obesity prevalence in males increasing from 48.5 to 51.0% ( < 0.001), whereas females exhibited a higher prevalence. Obesity was associated with younger adults (AOR 4.91, 95% CI 4.06–5.94) and those with hypertension (AOR 1.83, 95% CI 1.72–1.94). The risk of obesity showed an inverse correlation with a longer duration of diabetes (AOR 0.67, 95% CI 0.57–0.78). An inverse association was observed between smoking and obesity, with never-smokers having a greater risk of obesity compared to current smokers (AOR 1.69, 95% CI 1.48–1.92). Moreover, indoor occupations were associated with an increased rate of obesity (AOR 1.36, 95% CI 1.24–1.48).
The prevalence of obesity among T2DM patients in Thailand has continued to rise, particularly among men and young people. These findings suggest that T2DM obesity requires targeted lifestyle changes, weight management programs, and policy initiatives. Strengthening public health strategies that promote physical activity, dietary improvements, and access to effective diabetes management resources is critical for reducing obesity-related complications.
肥胖是一个新出现的公共卫生问题,也是2型糖尿病(T2DM)的一个重要危险因素。T2DM患者中肥胖患病率的不断上升会使疾病预后恶化,增加医疗费用,并增加心血管并发症的风险。认识T2DM患者肥胖的趋势及相关因素对于指导具体干预措施和公共卫生策略至关重要。本研究旨在分析2014年至2018年泰国T2DM患者肥胖患病率的趋势,并确定与肥胖相关的重要人口统计学、临床和生活方式因素。
这项序贯横断面研究利用了2014年和2018年泰国糖尿病/高血压数据库的二手数据。研究未纳入18岁以下个体或数据不完整者。描述性统计用于分析人口统计学特征和肥胖患病率,多变量逻辑回归用于确定与肥胖独立相关的因素。此外,线性回归分析评估了体重指数(BMI)与连续变量之间的关系,这些连续变量包括年龄、收缩压(SBP)和糖化血红蛋白(HbA1c)水平。
2014年共纳入32196例患者,2018年共纳入38119例患者。T2DM患者的肥胖患病率从2014年的49.9%升至2018年的51.1%,男性肥胖患病率从48.5%增至51.0%(P<0.001),而女性肥胖患病率更高。肥胖与较年轻的成年人(调整后比值比[AOR]4.91,95%置信区间[CI]4.06 - 5.94)和高血压患者(AOR 1.83,95% CI 1.72 - 1.94)相关。肥胖风险与糖尿病病程较长呈负相关(AOR 0.67,95% CI 0.57 - 0.78)。吸烟与肥胖之间存在负相关,从不吸烟者比当前吸烟者患肥胖症的风险更高(AOR 1.69,95% CI 1.48 - 1.92)。此外,室内工作与肥胖率增加相关(AOR 1.36,95% CI 1.24 - 1.48)。
泰国T2DM患者的肥胖患病率持续上升,尤其是在男性和年轻人中。这些发现表明,T2DM肥胖需要有针对性的生活方式改变、体重管理计划和政策举措。加强促进身体活动、改善饮食以及提供有效糖尿病管理资源的公共卫生策略对于减少肥胖相关并发症至关重要。