Blagden Sarah P, Dodd Kevin W, Brown Karen, Szabo Eva
Oncology Clinical Trials Office (OCTO), Department of Oncology, University of Oxford, Oxford, United Kingdom.
Division of Cancer Prevention, National Cancer Institute, Bethedsa, Maryland.
Cancer Prev Res (Phila). 2025 Sep 2;18(9):499-507. doi: 10.1158/1940-6207.CAPR-25-0035.
Precision prevention trials are biologically driven interception studies conducted in high cancer risk groups. These are smaller, potentially faster, cheaper, and more commercially attractive than traditional large-scale population prevention studies. In this article, we discuss the key challenges of conducting precision prevention research and their mitigations.
精准预防试验是在高癌症风险人群中开展的由生物学驱动的拦截研究。这些研究规模较小，可能速度更快、成本更低，且在商业上更具吸引力，相比传统的大规模人群预防研究而言。在本文中，我们讨论了开展精准预防研究的关键挑战及其应对措施。
