Krenzelok E P, Keller R, Stewart R D
Ann Emerg Med. 1985 Dec;14(12):1152-5. doi: 10.1016/s0196-0644(85)81019-2.
Oral activated charcoal usually is administered in toxic ingestions along with a cathartic. A study was done in volunteers to determine the rapidity of gastrointestinal transit when activated charcoal was administered with various cathartics. A control of activated charcoal was compared to the gastrointestinal transit times of activated charcoal plus the cathartics magnesium citrate, magnesium sulfate, or sorbitol. Activated charcoal alone produced a mean transit time of 23.5 hours; magnesium citrate catharsis occurred in 4.2 hours, magnesium sulfate catharsis occurred in 9.3 hours, and sorbitol catharsis occurred in 0.9 hours. Sorbitol clearly was the most rapidly acting cathartic.
口服活性炭通常在中毒摄入时与泻药一起使用。在志愿者中进行了一项研究，以确定活性炭与各种泻药一起使用时胃肠道转运的速度。将活性炭对照组与活性炭加泻药柠檬酸镁、硫酸镁或山梨醇的胃肠道转运时间进行比较。单独使用活性炭的平均转运时间为23.5小时；柠檬酸镁泻药作用时间为4.2小时，硫酸镁泻药作用时间为9.3小时，山梨醇泻药作用时间为0.9小时。山梨醇显然是作用最快的泻药。
